SCHEMBL4893583

SCHEMBL4893583

CC(C)(C)OC(=O)NCCCOC(=O)C(C)(C)Br

nearest known ligand 0.56

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CA12 O43570 7/20 0.56
CA1 P00915 7/20 0.56
CA2 P00918 7/20 0.56
CA9 Q16790 7/20 0.56
TDP1 Q9NUW8 1/20 0.54
MEN1 O00255 1/20 0.51
GAA P10253 1/20 0.51
KMT2A Q03164 1/20 0.51
MAOA P21397 1/20 0.48
MAOB P27338 1/20 0.48
IDO1 P14902 1/20 0.43
STK17B O94768 1/20 0.41
STK17A Q9UEE5 1/20 0.41
ACHE P22303 6/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12284963 0.92 CA12 (0.49) CA12CA1CA2CA9TDP1
SCHEMBL1901959 0.90 IDO1 (0.51) CA12CA1CA2CA9TDP1
SCHEMBL21441648 0.88 CA12 (0.46) CA12CA1CA2CA9TDP1
SCHEMBL21878211 0.87 CA12 (0.59) CA12CA1CA2CA9TDP1
SCHEMBL19263787 0.86 CA12 (0.47) CA12CA1CA2CA9TDP1
SCHEMBL6937740 0.83 CA12 (0.62) CA12CA1CA2CA9TDP1
SCHEMBL1063374 0.81 CA12 (0.60) CA12CA1CA2CA9TDP1
SCHEMBL6937743 0.81 CA12 (0.60) CA12CA1CA2CA9TDP1
SCHEMBL4112468 0.81 CA12 (0.60) CA12CA1CA2CA9TDP1
SCHEMBL35211336 0.80 CA12 (0.59) CA12CA1CA2CA9TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9200104-B2 Polymer WARWICK EFFECT POLYMERS LIMITED (GB) 2015-12-01 US disclosed
US-9200104-B2 Polymer WARWICK EFFECT POLYMERS LIMITED (GB) 2015-12-01 US disclosed
US-20130295040-A1 POLYMER WARWICK EFFECT POLYMERS LTD (US) 2013-11-07 US disclosed
US-20130295040-A1 POLYMER WARWICK EFFECT POLYMERS LTD (US) 2013-11-07 US disclosed
US-8436104-B2 Polymer WARWICK EFFECT POLYMERS LIMITED (GB) 2013-05-07 US disclosed
US-8436104-B2 Polymer WARWICK EFFECT POLYMERS LIMITED (GB) 2013-05-07 US disclosed
US-8436104-B2 Polymer WARWICK EFFECT POLYMERS LIMITED (GB) 2013-05-07 US disclosed
US-8197847-B2 Process for making polymers and supports comprising pendant sugar side groups WARWICK EFFECT POLYMERS LTD. (GB) 2012-06-12 US disclosed
US-20090082224-A1 POLYMERS WARWICK EFFECT POLYMERS LIMITED (GB) 2009-03-26 US disclosed
US-20080300348-A1 Polymer WARWICK EFFECT POLYMERS LIMITED 2008-12-04 US disclosed
US-20080300348-A1 Polymer WARWICK EFFECT POLYMERS LIMITED 2008-12-04 US disclosed
EP-1784430-A1 LIVING RADICAL POLYMERIZATION INITIATOR COMPRISING A FUNCTIONAL GROUP CAPABLE OF REACTING WITH POLYEPTIDES OR THE LIKE, COMB POLYMER OBTAINED THEREWITH , POLYPEPTIDE CONJUGATES AND DRUGS OBTAINED THEREFROM. Warwick Effect Polymers Limited (GB) 2007-05-16 EP disclosed
WO-2006003352-A1 LIVING RADICAL POLYMERIZATION INITIATOR COMPRISING A FUNCTIONAL GROUP CAPABLE OF REACTING WITH POLYEPTIDES OR THE LIKE, COMB POLYMER OBTAINED THEREWITH, POLYPEPTIDE CONJUGATES AND DRUGS OBTAINED THEREFROM WARWICK EFFECT POLYMERS LIMITED (GB) 2006-01-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130295040-A1 POLYMER PCNA, PARG, COASY CA12 1397/4885CA1 2153/4885CA2 3402/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.