⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2993 | 0.74 | — | — | |
| SCHEMBL9452523 | 0.74 | — | — | |
| SCHEMBL209013 | 0.74 | — | — | |
| SCHEMBL185154 | 0.74 | — | — | |
| SCHEMBL1378978 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL28158524 | 0.72 | — | — | |
| SCHEMBL16289085 | 0.70 | — | — | |
| SCHEMBL4794388 | 0.70 | — | — | |
| SCHEMBL1198206 | 0.70 | APP (0.38) | — | |
| SCHEMBL483062 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080213213-A1 | Method For the Treatment of Myelodysplastic Syndromes Using (+)-2-[1-(3-Ethoxy-4-Methoxyphenyl)-2-Methylsulfonylethyl]-4-Acetylaminoisoindoline-1,3-Dione | CELGENE CORPORATION | 2008-09-04 | — | — | US | disclosed |