Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ZDHHC20 | Q5W0Z9 | 2/20 | 0.44 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 2/20 | 0.42 |
| ▸ | APP | P05067 | 4/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | DGKA | P23743 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4891840 | 0.98 | HCAR2 (0.51) | HCAR2ATMHTTMAPTMEN1 | |
| SCHEMBL4889702 | 0.94 | ATM (0.56) | HCAR2ATMHTTMAPTMEN1 | |
| SCHEMBL35576 | 0.94 | ATM (0.56) | HCAR2ATMHTTMAPTMEN1 | |
| SCHEMBL6466648 | 0.91 | HCAR2 (0.54) | HCAR2ATMHTTMAPTZDHHC20 | |
| SCHEMBL4892532 | 0.90 | ATM (0.61) | HCAR2ATMHTTMAPTZDHHC20 | |
| SCHEMBL3457992 | 0.90 | HCAR2 (0.64) | HCAR2ATMHTTMAPTZDHHC20 | |
| SCHEMBL15229292 | 0.90 | HCAR2 (0.64) | HCAR2ATMHTTMAPTZDHHC20 | |
| SCHEMBL29341 | 0.90 | HCAR2 (0.64) | HCAR2ATMHTTMAPTZDHHC20 | |
| SCHEMBL8380051 | 0.90 | HCAR2 (0.64) | HCAR2ATMHTTMAPTZDHHC20 | |
| SCHEMBL2903635 | 0.90 | HCAR2 (0.64) | HCAR2ATMHTTMAPTZDHHC20 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080293872-A1 | ADHESIVES, SEALANTS AND COATINGS CONTAINING GLASS PARTICLES AS A FILLER | HENKEL AG & CO. KGAA (DE) | 2008-11-27 | — | — | US | disclosed |
| US-20080287574-A1 | ADHESIVES, SEALANTS AND COATINGS CONTAINING GLASS PARTICLES AS A FILLER | HENKEL AG & CO. KGAA (DE) | 2008-11-20 | — | — | US | disclosed |