Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 1/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.41 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | FBP1 | P09467 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.31 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4722034 | 0.94 | SCN1A (0.42) | SCN1ASCN2ASCN3ATLR8HTR7 | |
| SCHEMBL4723360 | 0.91 | SCN1A (0.40) | SCN1ASCN2ASCN3ATLR8HTR7 | |
| SCHEMBL4723376 | 0.87 | SCN1A (0.40) | SCN1ASCN2ASCN3ATLR8HTR7 | |
| SCHEMBL4724814 | 0.86 | SCN1A (0.44) | SCN1ASCN2ASCN3AHTR7L3MBTL1 | |
| SCHEMBL30514164 | 0.84 | SCN1A (0.38) | SCN1ASCN2ASCN3ATLR8HTR7 | |
| Hydrochloric Acid SCHEMBL28694374 | 0.81 | HDAC1 (0.37) | SCN1ASCN2ASCN3ATLR8L3MBTL1 | |
| SCHEMBL10707298 | 0.81 | TLR8 (0.37) | SCN1ASCN2ASCN3ATLR8HTR7 | |
| SCHEMBL4720415 | 0.79 | SCN1A (0.42) | SCN1ASCN2ASCN3AHTR7L3MBTL1 | |
| SCHEMBL4722623 | 0.78 | SCN1A (0.43) | SCN1ASCN2ASCN3AHTR7FBP1 | |
| SCHEMBL4724796 | 0.78 | PPARG (0.40) | SCN1ASCN2ASCN3ATLR8HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104254534-B | Modulators of HEC1 activity and methods thereof | 泰纬生命科技股份有限公司 | 2017-07-14 | — | — | CN | disclosed |
| US-7357989-B2 | Di(het)arylaminothiazole derivatives and their use in organic light-emitting diodes(OLEDs) and organic photovoltaic components | OSRAM OPTO SEMICONDUCTORS GMBH (DE) | 2008-04-15 | — | — | US | disclosed |
| US-20040028943-A1 | Di(het)arylaminothiazole derivatives and their use in organic light-emitting diodes(oleds) and organic photovoltaic components | OSRAM OLED GMBH (DE) | 2004-02-12 | — | — | US | disclosed |