SCHEMBL4895301

SCHEMBL4895301

[c]1ccc(-c2c3ccccc3c(-c3ccc4ccccc4c3)c3ccccc23)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE9A O76083 1/20 0.42
ESR1 P03372 3/20 0.41
ESR2 Q92731 3/20 0.41
GSTP1 P09211 1/20 0.41
ALOX5 P09917 2/20 0.41
HSD17B1 P14061 1/20 0.39
HSD17B2 P37059 1/20 0.39
HDAC4 P56524 1/20 0.39
HDAC2 Q92769 1/20 0.39
HDAC8 Q9BY41 1/20 0.39
IKBKB O14920 1/20 0.38
GPR84 Q9NQS5 1/20 0.38
NISCH Q9Y2I1 1/20 0.38
ACMSD Q8TDX5 1/20 0.38
CYP1A2 P05177 2/20 0.37
CYP11B1 P15538 2/20 0.37
CYP11B2 P19099 2/20 0.37
CYP17A1 P05093 1/20 0.37
CYP19A1 P11511 1/20 0.37
CYP1A1 P04798 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2379728 0.86 ESR1 (0.52) PDE9AESR1ESR2GSTP1ALOX5
SCHEMBL36279 0.86 ESR1 (0.52) PDE9AESR1ESR2GSTP1ALOX5
SCHEMBL29350362 0.86 ESR1 (0.52) PDE9AESR1ESR2GSTP1ALOX5
SCHEMBL16628542 0.86 PDE9A (0.40) PDE9AESR1ESR2GSTP1ALOX5
SCHEMBL30150716 0.84 ESR1 (0.57) PDE9AESR1ESR2GSTP1ALOX5
SCHEMBL30730877 0.84 ESR1 (0.53) PDE9AESR1ESR2GSTP1ALOX5
SCHEMBL5502280 0.84 ESR1 (0.53) PDE9AESR1ESR2GSTP1ALOX5
SCHEMBL2089825 0.84 ESR1 (0.57) PDE9AESR1ESR2GSTP1ALOX5
SCHEMBL25060858 0.84 ESR1 (0.50) PDE9AESR1ESR2GSTP1ALOX5
SCHEMBL25566510 0.84 ESR1 (0.50) PDE9AESR1ESR2GSTP1ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8217570-B2 Anthracene derivative and organic electroluminescent element using the same IDEMITSU KOSAN CO., LTD. (JP) 2012-07-10 US disclosed
US-20080111473-A1 Anthracene Derivative and Organic Electroluminescent Element Using the Same IDEMITSU KOSAN CO., LTD. (JP) 2008-05-15 US disclosed