⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4919332 | 0.77 | TOP2A (0.31) | — | |
| SCHEMBL4919336 | 0.77 | TOP2A (0.31) | — | |
| SCHEMBL782982 | 0.76 | — | — | |
| SCHEMBL782983 | 0.76 | — | — | |
| SCHEMBL22907438 | 0.75 | PPM1D (0.31) | — | |
| SCHEMBL783602 | 0.75 | PPM1D (0.31) | — | |
| SCHEMBL782711 | 0.75 | PPM1D (0.31) | — | |
| SCHEMBL18540559 | 0.75 | PPM1D (0.31) | — | |
| SCHEMBL18540525 | 0.75 | PPM1D (0.31) | — | |
| SCHEMBL14107856 | 0.74 | PPM1D (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080176813-A1 | CARBOCYCLIC NUCLEOSIDES AND PROCESS FOR OBTAINING SUCH | STICHTING REGA VZW (BE) | 2008-07-24 | — | — | US | disclosed |
| EP-1210347-B1 | CARBOCYCLIC NUCLEOSIDES AND PROCESS FOR OBTAINING SUCH | STICHTING REGA V Z W (BE) | 2004-06-23 | — | — | EP | disclosed |