Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 5/20 | 0.48 |
| ▸ | CDK2 | P24941 | 5/20 | 0.48 |
| ▸ | CDK6 | Q00534 | 12/20 | 0.44 |
| ▸ | CCND3 | P30281 | 12/20 | 0.44 |
| ▸ | CDK4 | P11802 | 9/20 | 0.44 |
| ▸ | CCND1 | P24385 | 9/20 | 0.44 |
| ▸ | EGFR | P00533 | 3/20 | 0.41 |
| ▸ | TYK2 | P29597 | 3/20 | 0.39 |
| ▸ | CDK9 | P50750 | 8/20 | 0.39 |
| ▸ | CCNK | O75909 | 4/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 4/20 | 0.39 |
| ▸ | CDK7 | P50613 | 4/20 | 0.39 |
| ▸ | CCNH | P51946 | 4/20 | 0.39 |
| ▸ | CDK1 | P06493 | 3/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.39 |
| ▸ | CCND2 | P30279 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4899105 | 0.99 | CCNA2 (0.46) | CCNA2CDK2CDK6CCND3CDK4 | |
| SCHEMBL4902937 | 0.90 | CDK6 (0.49) | CCNA2CDK2CDK6CCND3CDK4 | |
| Hydrochloric Acid SCHEMBL4892083 | 0.88 | CCND3 (0.48) | CCNA2CDK2CDK6CCND3CDK4 | |
| SCHEMBL4893114 | 0.87 | CDK2 (0.45) | CCNA2CDK2CDK6CCND3CDK4 | |
| SCHEMBL4904679 | 0.86 | CDK4 (0.46) | CCNA2CDK2CDK6CCND3CDK4 | |
| SCHEMBL27662832 | 0.86 | CCNA2 (0.41) | CCNA2CDK2CDK6CCND3CDK4 | |
| Hydrochloric Acid SCHEMBL27682318 | 0.86 | CDK2 (0.45) | CCNA2CDK2CDK6CCND3CDK4 | |
| SCHEMBL4892130 | 0.85 | CCNA2 (0.44) | CCNA2CDK2CDK6CCND3CDK4 | |
| Hydrochloric Acid SCHEMBL4899525 | 0.85 | CCNA2 (0.41) | CCNA2CDK2CDK6CCND3CDK4 | |
| Hydrochloric Acid SCHEMBL28760948 | 0.85 | CDK4 (0.46) | CCNA2CDK2CDK6CCND3CDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080108600-A1 | Polycyclic Pyridines as Potassium Ion Channel Modulators | ICAGEN, INC. (US) | 2008-05-08 | — | — | US | disclosed |
| EP-1737852-A2 | POLYCYCLIC PYRIDINES AS POTASSIUM ION CHANNEL MODULATORS | Icagen, Inc. (US) | 2007-01-03 | — | — | EP | disclosed |
| WO-2005100349-A2 | POLYCYCLIC PYRIDINES AS POTASSIUM ION CHANNEL MODULATORS | ICAGEN, INC. (US) | 2005-10-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080108600-A1 | Polycyclic Pyridines as Potassium Ion Channel Modulators | KCNJ2, KCNH2, KCNQ1 | CCNA2 4359/4885CDK2 3182/4885CDK6 2720/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.