Dalapon

Dalapon

SCHEMBL4895986

CC(Cl)(Cl)C(=O)O.CC(Cl)(Cl)C(=O)O

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.57
ALDH1A1 P00352 3/20 0.57
TP53 P04637 1/20 0.57
CYP2D6 P10635 2/20 0.40
CYP2C19 P33261 2/20 0.40
HIF1A Q16665 1/20 0.40
THRB P10828 1/20 0.38
FFAR3 O14843 1/20 0.36
LCK P06239 1/20 0.36
FYN P06241 1/20 0.36
HMGCR P04035 1/20 0.35
CHRM1 P11229 1/20 0.35
TBXA2R P21731 1/20 0.35
ADRA1A P35348 1/20 0.35
CYP1A2 P05177 2/20 0.35
MEN1 O00255 1/20 0.32
CYP3A4 P08684 1/20 0.32
MAPT P10636 1/20 0.32
KMT2A Q03164 1/20 0.32
PPARA Q07869 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dalapon SCHEMBL45164 1.00
Dalapon SCHEMBL613968 0.96
Dalapon SCHEMBL4441559 0.96
Dalapon SCHEMBL28068996 0.96 TSHR (0.53) TSHRALDH1A1TP53CYP2D6CYP2C19
Dalapon SCHEMBL4446142 0.96
Dalapon SCHEMBL11048266 0.96
Dalapon SCHEMBL4453180 0.96
Dalapon SCHEMBL30881518 0.96
Dalapon SCHEMBL2586474 0.96
Dalapon SCHEMBL4444190 0.96

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 206 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3746505-B1 COMPOSITION, POLYMER COMPOSITE ARTICLE FORMED THEREWITH, AND METHOD OF PREPARING SAME DOW SILICONES CORP (US) 2024-06-26 EP disclosed
EP-3906245-B1 MULTIFUNCTIONAL ORGANOSILICON COMPOUND AND RELATED METHODS, COMPOUNDS, AND COMPOSITIONS DOW SILICONES CORP (US) 2024-05-29 EP disclosed
US-20240124709-A1 COMPOSITION, POLYMER COMPOSITE ARTICLE FORMED THEREWITH, AND METHOD OF PREPARING SAME DOW GLOBAL TECHNOLOGIES LLC 2024-04-18 US disclosed
US-11884821-B2 Composition, polymer composite article formed therewith, and method of preparing same DOW SILICONES CORPORATION (US) 2024-01-30 US disclosed
WO-2023215360-A1 SILICONE-POLYETHER COPOLYMER, SEALANTS COMPRISING SAME, AND RELATED METHODS DOW SILICONES CORPORATION (US) 2023-11-09 WO disclosed
US-11807775-B2 Silicone-organic copolymer, sealants comprising same, and related methods DOW SILICONES CORPORATION (US) 2023-11-07 US disclosed
US-11760841-B2 Silicone-polycarbonate copolymer, sealants comprising same, and related methods DOW SILICONES CORPORATION (US) 2023-09-19 US disclosed
CN-113272364-B Silicone-polyacrylate copolymers, sealants including silicone-polyacrylate copolymers, and related methods 美国陶氏有机硅公司 2023-03-24 CN disclosed
CN-113272363-B Silicone-organic copolymers, sealants including silicone-organic copolymers, and related methods 美国陶氏有机硅公司 2023-02-17 CN disclosed
EP-3898779-B1 SILICONE-POLYESTER COPOLYMER, SEALANTS COMPRISING SAME, AND RELATED METHODS DOW SILICONES CORP (US) 2023-02-08 EP disclosed
EP-0413730-A1 HERBICIDAL PYRIDINESULFONYLUREAS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-02-27 EP disclosed
CN-1045786-A SELECTIVE OXABICYCLOALKANES DU PONT (US) 1990-10-03 CN disclosed
CN-1044818-A HERBICIDAL OXABICYCLONONANE ETHERS DU PONT (US) 1990-08-22 CN disclosed
EP-0003890-B2 Herbicidal pyridine compounds and herbicidal compositions containing them IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-04-04 EP disclosed
CN-1038281-A HERBICIDAL OXABICYCLOALKAWE ETHERS DU PONT (US) 1989-12-27 CN disclosed
WO-1989010694-A1 HERBICIDAL PYRIDINESULFONYLUREAS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1989-11-16 WO disclosed
CN-1035287-A The neighbour of weeding-methoxycarbonyl sulfonylurea DU PONT (US) 1989-09-06 CN disclosed
CN-87107320-A Herbicidal pyridine sulfonylureas 1988-12-07 CN disclosed
CN-87102603-A Sulfonamides herbicide 1987-10-21 CN disclosed
US-4121767-A Mobile agricultural sprayer with additive concentration control JENSEN RICHARD 1978-10-24 US disclosed