Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.67 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA3 | P07451 | 1/20 | 0.54 |
| ▸ | CA4 | P22748 | 1/20 | 0.54 |
| ▸ | CA6 | P23280 | 1/20 | 0.54 |
| ▸ | CA5A | P35218 | 1/20 | 0.54 |
| ▸ | CA7 | P43166 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.54 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | CRHBP | P24387 | 2/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11685838 | 0.86 | KMT2A (0.55) | KMT2ACA12CA1CA2CA3 | |
| SCHEMBL5147605 | 0.84 | KMT2A (0.93) | KMT2AMEN1LMNAALDH1A1MAPT | |
| SCHEMBL25348064 | 0.81 | TP53 (0.61) | KMT2ACA12CA1CA2CA3 | |
| SCHEMBL28643872 | 0.81 | POLB (0.54) | KMT2ACA12CA1CA2CA3 | |
| SCHEMBL2520150 | 0.78 | MEN1 (0.66) | KMT2ACA12CA1CA2CA3 | |
| SCHEMBL8577911 | 0.77 | C1R (0.49) | KMT2ACA12CA1CA2CA3 | |
| SCHEMBL5316222 | 0.77 | KMT2A (0.74) | KMT2AMEN1LMNAALDH1A1MAPT | |
| SCHEMBL8576910 | 0.76 | CA12 (0.41) | KMT2ACA12CA1CA2CA3 | |
| SCHEMBL6611414 | 0.75 | MAPT (0.61) | KMT2AMEN1LMNAALDH1A1MAPT | |
| SCHEMBL7571544 | 0.75 | MEN1 (0.61) | KMT2ACA12CA1CA2CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080293970-A1 | Process for Synthesis of 4-4'-Diamino-Diphenyl-Sulfone | LUNDBECK PHARMACEUTICALS ITALY S.P.A. | 2008-11-27 | — | — | US | disclosed |