SCHEMBL4896953

SCHEMBL4896953

Oc1ccc2ccccc2c1S

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN22 Q9Y2R2 1/20 0.60
POLB P06746 1/20 0.56
HSD17B10 Q99714 3/20 0.54
CYP1A2 P05177 2/20 0.54
USP2 O75604 1/20 0.54
PAK1 Q13153 1/20 0.54
CYP2C9 P11712 1/20 0.54
CYP2C19 P33261 1/20 0.54
KDM4E B2RXH2 4/20 0.50
ALDH1A1 P00352 3/20 0.50
TDP1 Q9NUW8 3/20 0.50
MAPT P10636 3/20 0.50
GAA P10253 2/20 0.50
CYP2A6 P11509 1/20 0.50
TSHR P16473 1/20 0.50
TAAR1 Q96RJ0 1/20 0.50
ERN1 O75460 1/20 0.50
IDO1 P14902 1/20 0.48
HPRT1 P00492 1/20 0.46
THRB P10828 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10688283 1.00 PTPN22 (0.60) PTPN22POLBHSD17B10CYP1A2USP2
SCHEMBL11600079 0.94 PTPN22 (0.54) PTPN22POLBHSD17B10CYP1A2USP2
Tetrabuthylammonium SCHEMBL10790354 0.80 CYP1A2 (0.41) PTPN22POLBHSD17B10CYP1A2USP2
SCHEMBL29362162 0.75 PTPN22 (0.65) PTPN22POLBHSD17B10CYP1A2USP2
SCHEMBL28483 0.75 PTPN22 (1.00) PTPN22POLBHSD17B10CYP1A2USP2
Hydrochloric Acid SCHEMBL27843667 0.75 PTPN22 (1.00) PTPN22POLBHSD17B10CYP1A2USP2
SCHEMBL15400598 0.75 PTPN22 (0.65) PTPN22POLBHSD17B10CYP1A2USP2
Hydrochloric Acid SCHEMBL28347175 0.75 PTPN22 (1.00) PTPN22POLBHSD17B10CYP1A2USP2
SCHEMBL29613822 0.75 PTPN22 (1.00) PTPN22POLBHSD17B10CYP1A2USP2
SCHEMBL29027 0.75 PTPN22 (0.65) PTPN22POLBHSD17B10CYP1A2USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0292176-A2 Organo-metal compositions, preparation and use IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-11-23 EP claimed
JP-57179154-A None JP disclosed
JP-51113857-A None JP disclosed
WO-2017172979-A1 SUBSTITUTED QUINAZOLINE COMPOUNDS AND METHODS OF USE ARAXES PHARMA LLC (US) 2017-10-05 WO disclosed
WO-2016161033-A1 METHODS FOR MAKING OLIGOMERIC ACIDS AND ROSIN OIL FROM CRUDE TALL OIL GEORGIA-PACIFIC CHEMICALS LLC (US) 2016-10-06 WO disclosed
US-20080097062-A1 Method of Producing Disproportionated Rosin ALBEMARLE CORPORATION (US) 2008-04-24 US disclosed
EP-1846528-A1 METHOD OF PRODUCING DISPROPORTIONATED ROSIN ALBEMARLE CORPORATION (US) 2007-10-24 EP disclosed
WO-2006085873-A1 METHOD OF PRODUCING DISPROPORTIONATED ROSIN ALBEMARLE CORPORATION (US) 2006-08-17 WO disclosed
EP-0292176-A2 Organo-metal compositions, preparation and use IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-11-23 EP disclosed
JP-S57179154-A PREPARATION OF 2,2'-DIHYDROXY-1,1'-DINAPHTHYL DISULFIDE MITSUI TOATSU CHEM INC 1982-11-04 JP disclosed
US-4070236-A Paper manufacture with improved retention agents SANDOZ LTD. (CH) 1978-01-24 US disclosed
JP-S51113857-A PROCESS FOR PREPARING NEAR INFRARED ABSORBENTS MITSUI TOATSU CHEM INC 1976-10-07 JP disclosed