Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 2/20 | 0.51 |
| ▸ | KDR | P35968 | 2/20 | 0.51 |
| ▸ | CNR2 | P34972 | 3/20 | 0.51 |
| ▸ | SMG1 | Q96Q15 | 1/20 | 0.49 |
| ▸ | SYK | P43405 | 3/20 | 0.47 |
| ▸ | CDC7 | O00311 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | PLK4 | O00444 | 1/20 | 0.41 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.41 |
| ▸ | STK16 | O75716 | 1/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.41 |
| ▸ | TYK2 | P29597 | 1/20 | 0.41 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.41 |
| ▸ | ULK3 | Q6PHR2 | 1/20 | 0.41 |
| ▸ | BMP2K | Q9NSY1 | 1/20 | 0.41 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4898702 | 0.86 | CNR2 (0.48) | CDK1KDRCNR2SYKNUAK1 | |
| SCHEMBL14045917 | 0.86 | CDK1 (0.52) | CDK1KDRCNR2SMG1SYK | |
| SCHEMBL4889093 | 0.85 | CNR2 (0.55) | CDK1KDRCNR2SMG1SYK | |
| SCHEMBL4893836 | 0.81 | CNR2 (0.63) | CNR2SYKCDC7MAOBGRM5 | |
| SCHEMBL14026150 | 0.78 | CNR2 (0.55) | CDK1CNR2SYKCDC7MAOB | |
| SCHEMBL14026161 | 0.76 | CNR2 (0.58) | CNR2SYKCDC7MAOBGRM5 | |
| SCHEMBL4896760 | 0.76 | CNR2 (0.53) | CNR2SYKMAOBGRM5CYP3A4 | |
| SCHEMBL14026176 | 0.76 | BRD4 (0.48) | CDK1KDRCNR2SMG1SYK | |
| SCHEMBL14026128 | 0.75 | CNR2 (0.54) | CNR2SYKMAOBGRM5CYP3A4 | |
| Hydrochloric Acid SCHEMBL4895824 | 0.75 | BRD4 (0.48) | CDK1KDRCNR2SMG1SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080261977-A1 | Pyrimidine Derivatives as Cannabinoid Receptor Modulators | GLAXO GROUP LIMITED (GB) | 2008-10-23 | — | — | US | disclosed |
| US-20080261977-A1 | Pyrimidine Derivatives as Cannabinoid Receptor Modulators | GLAXO GROUP LIMITED (GB) | 2008-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080261977-A1 | Pyrimidine Derivatives as Cannabinoid Receptor Modulators | CNR2, CNR1, P2RY2 | CDK1 347/4885KDR 1090/4885CNR2 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.