Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 11/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3603571 | 0.89 | HDAC1 (0.60) | HDAC1KCNH2NTRK1TRPV1MEN1 | |
| SCHEMBL3612433 | 0.88 | HDAC1 (0.58) | HDAC1KCNH2HPGDMAPTMEN1 | |
| SCHEMBL14182609 | 0.87 | HDAC1 (0.53) | HDAC1KCNH2TRPV1 | |
| SCHEMBL8242955 | 0.85 | HDAC1 (0.52) | HDAC1KCNH2NTRK1TRPV1 | |
| SCHEMBL5797598 | 0.85 | HDAC1 (0.60) | HDAC1KCNH2HPGDNTRK1TRPV1 | |
| SCHEMBL5802355 | 0.84 | HDAC1 (0.55) | HDAC1KCNH2MAPTMEN1KMT2A | |
| SCHEMBL4897229 | 0.84 | HDAC1 (0.52) | HDAC1KCNH2POLBHPGDNTRK1 | |
| SCHEMBL4894599 | 0.84 | HDAC1 (0.56) | HDAC1KCNH2POLBHPGDMAPT | |
| SCHEMBL4890450 | 0.84 | HDAC1 (0.54) | HDAC1KCNH2 | |
| SCHEMBL4893491 | 0.81 | KMT2A (0.58) | HDAC1POLBHPGDMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080119451-A1 | Novel Benzamide Derivatives | ASTRAZENECA AB (SE) | 2008-05-22 | — | — | US | disclosed |
| WO-2006077387-A2 | NOVEL BENZAMIDE DERIVATIVES | ASTRAZENECA AB (SE) | 2006-07-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080119451-A1 | Novel Benzamide Derivatives | HDAC1, HDAC11, HDAC2 | HDAC1 1/4885KCNH2 1230/4885POLB 254/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.