Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 16/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 16/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 13/20 | 0.62 |
| ▸ | HDAC8 | Q9BY41 | 13/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 12/20 | 0.62 |
| ▸ | HDAC7 | Q8WUI4 | 12/20 | 0.62 |
| ▸ | HDAC4 | P56524 | 11/20 | 0.62 |
| ▸ | HDAC5 | Q9UQL6 | 11/20 | 0.62 |
| ▸ | HDAC9 | Q9UKV0 | 11/20 | 0.62 |
| ▸ | HDAC10 | Q969S8 | 10/20 | 0.62 |
| ▸ | HDAC11 | Q96DB2 | 10/20 | 0.62 |
| ▸ | TUBB4A | P04350 | 7/20 | 0.62 |
| ▸ | TUBB | P07437 | 7/20 | 0.62 |
| ▸ | TUBA3C | P0DPH7 | 7/20 | 0.62 |
| ▸ | TUBA1B | P68363 | 7/20 | 0.62 |
| ▸ | TUBA4A | P68366 | 7/20 | 0.62 |
| ▸ | TUBB4B | P68371 | 7/20 | 0.62 |
| ▸ | TUBB3 | Q13509 | 7/20 | 0.62 |
| ▸ | TUBB2A | Q13885 | 7/20 | 0.62 |
| ▸ | TUBB8 | Q3ZCM7 | 7/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4886860 | 0.93 | HDAC2 (0.60) | HDAC2HDAC1HDAC6HDAC8HDAC3 | |
| SCHEMBL4896217 | 0.91 | HDAC2 (0.68) | HDAC2HDAC1HDAC6HDAC8HDAC3 | |
| SCHEMBL4896680 | 0.87 | HDAC1 (0.54) | HDAC2HDAC1HDAC6HDAC8HDAC3 | |
| SCHEMBL4886855 | 0.86 | HDAC1 (0.65) | HDAC2HDAC1HDAC6HDAC8HDAC3 | |
| SCHEMBL4900809 | 0.82 | HDAC1 (0.51) | HDAC2HDAC1HDAC6HDAC8HDAC3 | |
| SCHEMBL4896689 | 0.81 | HDAC1 (0.54) | HDAC2HDAC1HDAC6HDAC8HDAC3 | |
| SCHEMBL4900832 | 0.80 | HDAC1 (0.57) | HDAC2HDAC1HDAC6HDAC8HDAC3 | |
| SCHEMBL4896987 | 0.79 | HDAC1 (0.54) | HDAC2HDAC1HDAC6HDAC8HDAC3 | |
| SCHEMBL4898161 | 0.78 | HDAC1 (0.54) | HDAC2HDAC1HDAC6HDAC8HDAC3 | |
| SCHEMBL4899156 | 0.77 | HDAC8 (1.00) | HDAC2HDAC1HDAC6HDAC8HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080275023-A1 | N-Hydroxyamides Omege-Substituted with Tricyclic Groups as Histone Deacetylase Inhibitors, Their Preparation and Use in Pharmaceutical Formulations | MENARIN INTERNATIONAL OPERATIONS LUXEMBOURG S.A. (LU) | 2008-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080275023-A1 | N-Hydroxyamides Omege-Substituted with Tricyclic Groups as Histone Deacetylase Inhibitors, Their Preparation and Use in Pharmaceutical Formulations | HDAC8, HDAC2, HDAC7 | HDAC2 2/4885HDAC1 4/4885HDAC6 12/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.