⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4896655 | 0.87 | — | — | |
| SCHEMBL17556595 | 0.84 | — | — | |
| SCHEMBL17556456 | 0.84 | — | — | |
| SCHEMBL7090382 | 0.84 | — | — | |
| SCHEMBL4486839 | 0.80 | — | — | |
| SCHEMBL9851 | 0.70 | — | — | |
| SCHEMBL7096752 | 0.70 | — | — | |
| SCHEMBL1470768 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL19946015 | 0.67 | — | — | |
| Bicarbonate SCHEMBL3824750 | 0.65 | CA1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114805346-A | Heterocyclic derivative, preparation method and application thereof | 成都硕德药业有限公司 | 2022-07-29 | — | — | CN | claimed |
| CN-114560855-A | Cycloalkylcarboxamide derivative, preparation method and application thereof | 成都苑东生物制药股份有限公司 | 2022-05-31 | — | — | CN | claimed |
| US-20240239778-A1 | GRISEOFULVIN COMPOUND AND PHARMACEUTICAL USE THEREOF | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2024-07-18 | — | — | US | disclosed |
| CN-118344370-A | Isoindolinone and indazole compounds for EGFR degradation | C4医药公司 | 2024-07-16 | — | — | CN | disclosed |
| WO-2024148149-A2 | COMPOSITIONS AND METHODS FOR CONTROLLING GLUCOSE LEVELS | SIRTSEI PHARMACEUTICALS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |
| US-11993593-B2 | Griseofulvin compound and pharmaceutical use thereof | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2024-05-28 | — | — | US | disclosed |
| CN-114901277-B | Isoindolinone and indazole compounds for EGFR degradation | C4医药公司 | 2024-05-17 | — | — | CN | disclosed |
| US-20240158418-A1 | EGFR Degraders to Treat Cancer Metastasis to the Brain or CNS | C4 THERAPEUTICS, INC. (US) | 2024-05-16 | — | — | US | disclosed |
| EP-4359409-A1 | DEGRADER COMPOUNDS AND USES THEREOF | Calico Life Sciences LLC (US) | 2024-05-01 | — | — | EP | disclosed |
| US-11964957-B2 | Pyrazole derivative and harmful organism-controlling agent | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2024-04-23 | — | — | US | disclosed |
| EP-3808738-B1 | PYRAZOLE DERIVATIVE AND HARMFUL ORGANISM-CONTROLLING AGENT | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2024-04-17 | — | — | EP | disclosed |
| CN-102471235-A | Radiolabelling method using cycloalkyl groups | BAYER SCHERING PHARMA AG | 2012-05-23 | — | — | CN | disclosed |
| US-20080009512-A1 | Tetrahydroquinolones and Aza-Analogues Thereof for Use as Dpp-IV Inhibitors in the Treatment of Diabetes | ASTRAZENECA AB (SE) | 2008-01-10 | — | — | US | disclosed |
| EP-1758863-A1 | TETRAHYDROQUINOLONES AND AZA-ANALOGUES THEREOF FOR USE AS DPP-IV INHIBITORS IN THE TREATEMENT OF DIABETES | AstraZeneca AB (SE) | 2007-03-07 | — | — | EP | disclosed |
| CN-1295213-C | Fluorinated cycloalkyl-derivatized benzoylguanidines, process for their preparation, their uses as medicament | AVENTIS PHARMA GMBH (DE) | 2007-01-17 | — | — | CN | disclosed |
| WO-2005123685-A1 | TETRAHYDROQUINOLONES AND AZA-ANALOGUES THEREOF FOR USE AS DPP-IV INHIBITORS IN THE TREATEMENT OF DIABETES | ASTRAZENECA AB (SE) | 2005-12-29 | — | — | WO | disclosed |
| CN-1659139-A | Fluorinated cycloalkyl-derived benzoylguanidines and their use as a medicament | AVENTIS PHARMA GMBH (DE) | 2005-08-24 | — | — | CN | disclosed |
| US-20030065189-A1 | Processes for producing 4-substituted benzopyran derivatives | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-04-03 | — | — | US | disclosed |
| US-6455708-B1 | SUCH AS 2,2-BIS(FLUOROMETHYL)-N-(2-CYANOETHYL)-6-TRIFLUOROMETHYL-2H-1-BENZOPYRAN-4 -CARBOXAMIDE; USEFUL AS MEDICINES, AGRICHEMICALS AND COSMETICS, AND CHEMICAL INTERMEDIATES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2002-09-24 | — | — | US | disclosed |
| EP-1120412-A1 | PROCESSES FOR THE PREPARATION OF 4-SUBSTITUTED BENZOPYRAN DERIVATIVES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2001-08-01 | — | — | EP | disclosed |