Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 19/20 | 0.68 |
| ▸ | BACE2 | Q9Y5Z0 | 15/20 | 0.62 |
| ▸ | CTSD | P07339 | 9/20 | 0.62 |
| ▸ | REN | P00797 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4511168 | 0.94 | BACE1 (0.64) | BACE1BACE2CTSDREN | |
| SCHEMBL4518549 | 0.86 | BACE1 (0.67) | BACE1BACE2CTSDREN | |
| SCHEMBL4527450 | 0.84 | BACE1 (0.68) | BACE1BACE2CTSDREN | |
| SCHEMBL4524188 | 0.84 | BACE1 (0.66) | BACE1BACE2CTSDREN | |
| SCHEMBL4518593 | 0.83 | BACE1 (0.66) | BACE1BACE2CTSDREN | |
| SCHEMBL4240351 | 0.82 | BACE1 (0.81) | BACE1BACE2CTSD | |
| SCHEMBL4513803 | 0.82 | BACE1 (0.67) | BACE1BACE2CTSDREN | |
| SCHEMBL23190467 | 0.81 | BACE1 (0.76) | BACE1BACE2CTSDREN | |
| SCHEMBL20814013 | 0.81 | BACE1 (1.00) | BACE1BACE2CTSDREN | |
| SCHEMBL4523967 | 0.80 | BACE1 (0.53) | BACE1BACE2CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008076046-A1 | NOVEL 2-AMINO-5, 5-DIARYL-IMIDAZOL-4-ONES | ASTRAZENECA AB (SE) | 2008-06-26 | — | — | WO | disclosed |