Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.39 |
| ▸ | EP300 | Q09472 | 1/20 | 0.37 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.36 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3652249 | 1.00 | TSHR (0.46) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL949869 | 1.00 | TSHR (0.46) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL7182170 | 1.00 | TSHR (0.46) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL7188921 | 1.00 | TSHR (0.46) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL7189741 | 1.00 | TSHR (0.46) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL7175478 | 1.00 | TSHR (0.46) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL951294 | 1.00 | TSHR (0.46) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL7175480 | 1.00 | TSHR (0.46) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL951295 | 1.00 | TSHR (0.46) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL949871 | 1.00 | TSHR (0.46) | TSHRTHRBFAAHTRPV1DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106062-B1 | Calcium channel blockers | DIAKRON PHARMACEUTICALS, INC. (US) | 2012-01-31 | — | — | US | disclosed |
| EP-0938842-B1 | Sustained release pheromone dispenser | SHINETSU CHEMICAL CO (JP) | 2003-10-15 | — | — | EP | disclosed |
| US-6355236-B2 | Sustained release pheromone formation | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2002-03-12 | — | — | US | disclosed |
| US-20010053372-A1 | SUSTAINED RELEASE PHEROMONE FORMATION | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2001-12-20 | — | — | US | disclosed |
| EP-0938842-A1 | Sustained release pheromone dispenser | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1999-09-01 | — | — | EP | disclosed |