Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.50 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.44 |
| ▸ | RELA | Q04206 | 2/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4891120 | 0.88 | SLC2A1 (0.62) | SLC2A1KDRSMN1; SMN2MEN1KMT2A | |
| SCHEMBL4902638 | 0.88 | SLC2A1 (0.42) | SLC2A1KDRNPC1RAB9ATNNI3K | |
| SCHEMBL4892301 | 0.86 | SLC2A1 (0.44) | SLC2A1KDRSMN1; SMN2MEN1KMT2A | |
| SCHEMBL4903020 | 0.84 | SLC2A1 (0.51) | SLC2A1KDRSMN1; SMN2MEN1KMT2A | |
| SCHEMBL4901584 | 0.84 | SLC2A1 (0.48) | SLC2A1KDRSMN1; SMN2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL4896691 | 0.83 | SLC2A1 (0.47) | SLC2A1KDRSMN1; SMN2MEN1KMT2A | |
| SCHEMBL4901286 | 0.82 | CCND3 (0.48) | EGFR | |
| SCHEMBL5311907 | 0.81 | SLC2A1 (0.40) | SLC2A1KDRSMN1; SMN2MEN1KMT2A | |
| SCHEMBL2226110 | 0.80 | SLC2A1 (0.44) | SLC2A1KDRSMN1; SMN2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL4901183 | 0.80 | SLC2A1 (0.39) | SLC2A1KDRSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080108600-A1 | Polycyclic Pyridines as Potassium Ion Channel Modulators | ICAGEN, INC. (US) | 2008-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080108600-A1 | Polycyclic Pyridines as Potassium Ion Channel Modulators | KCNJ2, KCNH2, KCNQ1 | SLC2A1 2369/4885KDR 3367/4885SMN1; SMN2 3670/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.