Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 4/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.43 |
| ▸ | CDK6 | Q00534 | 10/20 | 0.40 |
| ▸ | CCND3 | P30281 | 9/20 | 0.40 |
| ▸ | CCNK | O75909 | 6/20 | 0.40 |
| ▸ | CDK9 | P50750 | 6/20 | 0.40 |
| ▸ | CDK4 | P11802 | 6/20 | 0.39 |
| ▸ | CCND1 | P24385 | 6/20 | 0.39 |
| ▸ | CTSC | P53634 | 1/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.38 |
| ▸ | TYK2 | P29597 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4892385 | 0.99 | CDK2 (0.42) | CDK2CCNA2CDK6CCND3CCNK | |
| SCHEMBL5261263 | 0.90 | CCND3 (0.45) | CDK2CCNA2CDK6CCND3CCNK | |
| SCHEMBL5261566 | 0.89 | CDK4 (0.40) | CDK2CCNA2CDK6CCND3CCNK | |
| SCHEMBL4902677 | 0.85 | F10 (0.42) | SMN1; SMN2 | |
| SCHEMBL27663025 | 0.85 | POLB (0.39) | CDK2CCNA2CDK6CCND3CCNK | |
| SCHEMBL4894058 | 0.84 | CTSC (0.40) | CDK2CCNA2CDK6CCND3CCNK | |
| SCHEMBL5263950 | 0.84 | ATM (0.41) | SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4902864 | 0.83 | ATM (0.41) | SMN1; SMN2 | |
| SCHEMBL4891073 | 0.83 | CTSC (0.40) | CDK2CCNA2CDK6CCND3CCNK | |
| Hydrochloric Acid SCHEMBL27682306 | 0.82 | CDK4 (0.32) | CDK2CCNA2CDK6CCND3CCNK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080108600-A1 | Polycyclic Pyridines as Potassium Ion Channel Modulators | ICAGEN, INC. (US) | 2008-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080108600-A1 | Polycyclic Pyridines as Potassium Ion Channel Modulators | KCNJ2, KCNH2, KCNQ1 | CDK2 3182/4885CCNA2 4359/4885CDK6 2720/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.