Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 2/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL31338851 | 0.98 | CYP3A4 (0.44) | TDP1CYP3A4TRPA1ALDH1A1TSHR | |
| Bromide SCHEMBL31338846 | 0.87 | CYP3A4 (0.38) | TDP1CYP3A4TRPA1ALDH1A1TSHR | |
| SCHEMBL15876838 | 0.82 | CYP3A4 (0.50) | TDP1CYP3A4DRD1ESR1ESR2 | |
| SCHEMBL29517580 | 0.82 | CYP3A4 (0.50) | TDP1CYP3A4DRD1ESR1ESR2 | |
| SCHEMBL19626576 | 0.82 | CYP3A4 (0.50) | TDP1CYP3A4DRD1ESR1ESR2 | |
| Bromide SCHEMBL31338825 | 0.82 | TDP1 (0.41) | TDP1CYP3A4DRD1ESR1ESR2 | |
| SCHEMBL29827148 | 0.80 | TDP1 (0.39) | TDP1CYP3A4DRD1ESR1ESR2 | |
| SCHEMBL10581558 | 0.80 | CYP3A4 (0.48) | TDP1CYP3A4DRD1ESR1ESR2 | |
| Bromide SCHEMBL31338826 | 0.80 | TSHR (0.42) | TDP1CYP3A4TRPA1ALDH1A1TSHR | |
| SCHEMBL31253177 | 0.79 | TDP1 (0.38) | TDP1CYP3A4DRD1ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8404915-B2 | 1) at least one diaryl-substituted diphosphine ligand; 2) a chromium metal precursor; and 3) optionally, one or more activators | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2013-03-26 | — | — | US | disclosed |
| US-8404915-B2 | 1) at least one diaryl-substituted diphosphine ligand; 2) a chromium metal precursor; and 3) optionally, one or more activators | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2013-03-26 | — | — | US | disclosed |
| US-8404915-B2 | 1) at least one diaryl-substituted diphosphine ligand; 2) a chromium metal precursor; and 3) optionally, one or more activators | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2013-03-26 | — | — | US | disclosed |
| US-20080058486-A1 | Phosphine Ligand-Metal Compositions, Complexes, and Catalysts For Ethylene Trimerizations | SYMYX TECHNOLOGIES INC. | 2008-03-06 | — | — | US | disclosed |
| US-20080058486-A1 | Phosphine Ligand-Metal Compositions, Complexes, and Catalysts For Ethylene Trimerizations | SYMYX TECHNOLOGIES INC. | 2008-03-06 | — | — | US | disclosed |
| US-20080058486-A1 | Phosphine Ligand-Metal Compositions, Complexes, and Catalysts For Ethylene Trimerizations | SYMYX TECHNOLOGIES INC. | 2008-03-06 | — | — | US | disclosed |