Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 14/20 | 0.78 |
| ▸ | DPP8 | Q6V1X1 | 11/20 | 0.78 |
| ▸ | DPP7 | Q9UHL4 | 10/20 | 0.78 |
| ▸ | PREP | P48147 | 10/20 | 0.78 |
| ▸ | DPP9 | Q86TI2 | 7/20 | 0.78 |
| ▸ | FAP | Q12884 | 5/20 | 0.51 |
| ▸ | PITRM1 | Q5JRX3 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4896288 | 0.88 | DPP4 (1.00) | DPP4DPP8DPP7PREPDPP9 | |
| SCHEMBL4635523 | 0.88 | DPP4 (1.00) | DPP4DPP8DPP7PREPDPP9 | |
| SCHEMBL4892253 | 0.84 | DPP4 (1.00) | DPP4DPP8DPP7PREPDPP9 | |
| SCHEMBL4634954 | 0.75 | PREP (0.62) | DPP4DPP8DPP7PREPDPP9 | |
| SCHEMBL4634955 | 0.75 | PREP (0.62) | DPP4DPP8DPP7PREPDPP9 | |
| SCHEMBL4636747 | 0.74 | PREP (0.60) | DPP4DPP8DPP7PREPDPP9 | |
| SCHEMBL4636746 | 0.74 | PREP (0.60) | DPP4DPP8DPP7PREPDPP9 | |
| SCHEMBL3830920 | 0.74 | DPP4 (0.75) | DPP4DPP8DPP7PREPDPP9 | |
| Hydrochloric Acid SCHEMBL1347816 | 0.73 | DPP4 (0.74) | DPP4DPP8DPP7PREPDPP9 | |
| SCHEMBL2852327 | 0.73 | PREP (0.49) | DPP4DPP8DPP7PREPDPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080300251-A1 | Derivatives of 3-Azabicyclo[3.1.0] Hexane as Dipeptidyl Peptidase-IV Inhibitors | RANBAXY LABORATORIES LIMITED (IN) | 2008-12-04 | — | — | US | claimed |
| US-20080300251-A1 | Derivatives of 3-Azabicyclo[3.1.0] Hexane as Dipeptidyl Peptidase-IV Inhibitors | RANBAXY LABORATORIES LIMITED (IN) | 2008-12-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080300251-A1 | Derivatives of 3-Azabicyclo[3.1.0] Hexane as Dipeptidyl Peptidase-IV Inhibitors | DPP4, DPP3, DPP8 | DPP4 1/4885DPP8 3/4885DPP7 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.