Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 19/20 | 0.58 |
| ▸ | FNTB | P49356 | 19/20 | 0.58 |
| ▸ | PGGT1B | P53609 | 13/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4899984 | 0.87 | FNTA (0.56) | FNTAFNTBPGGT1B | |
| SCHEMBL4897491 | 0.86 | FNTA (0.57) | FNTAFNTBPGGT1B | |
| SCHEMBL4888295 | 0.85 | FNTA (0.59) | FNTAFNTBPGGT1B | |
| SCHEMBL454433 | 0.84 | FNTA (0.57) | FNTAFNTBPGGT1B | |
| SCHEMBL4889307 | 0.84 | FNTA (0.59) | FNTAFNTBPGGT1B | |
| SCHEMBL4894032 | 0.84 | FNTA (0.58) | FNTAFNTBPGGT1B | |
| SCHEMBL4897156 | 0.84 | FNTA (0.64) | FNTAFNTBPGGT1B | |
| SCHEMBL4896720 | 0.83 | FNTA (0.59) | FNTAFNTBPGGT1B | |
| SCHEMBL4899929 | 0.82 | FNTA (0.60) | FNTAFNTBPGGT1B | |
| SCHEMBL4893638 | 0.82 | FNTA (0.56) | FNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080312287-A1 | Compound and Methods For the Treatment of Cancer and Malaria | UNIVERSITY OF WASHINGTON (US) | 2008-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312287-A1 | Compound and Methods For the Treatment of Cancer and Malaria | AKR1C3, NR1H3, HCCS | FNTA 18/4885FNTB 38/4885PGGT1B 912/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.