Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.55 |
| ▸ | TYK2 | P29597 | 4/20 | 0.44 |
| ▸ | JUN | P05412 | 1/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | CDK4 | P11802 | 5/20 | 0.43 |
| ▸ | CCND1 | P24385 | 5/20 | 0.43 |
| ▸ | CCND3 | P30281 | 4/20 | 0.43 |
| ▸ | CDK6 | Q00534 | 4/20 | 0.43 |
| ▸ | CDK2 | P24941 | 4/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.43 |
| ▸ | PRKCI | P41743 | 1/20 | 0.43 |
| ▸ | CCNK | O75909 | 1/20 | 0.43 |
| ▸ | CDK9 | P50750 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 2/20 | 0.42 |
| ▸ | LYN | P07948 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4900079 | 0.90 | CYP1A1 (0.43) | CYP1A1CYP1A2CYP1B1TYK2CDK4 | |
| SCHEMBL27682405 | 0.85 | TYK2 (0.46) | CYP1A1CYP1A2CYP1B1TYK2CDK4 | |
| SCHEMBL28760940 | 0.85 | CDK4 (0.43) | CYP1A1CYP1A2CYP1B1CDK4CCND1 | |
| Hydrochloric Acid SCHEMBL4903105 | 0.85 | TYK2 (0.45) | CYP1A1CYP1A2CYP1B1TYK2CDK4 | |
| SCHEMBL4891175 | 0.85 | CDK6 (0.45) | CDK4CCND1CCND3CDK6CDK2 | |
| Hydrochloric Acid SCHEMBL4902843 | 0.84 | CDK6 (0.44) | CDK4CCND1CCND3CDK6CDK2 | |
| Hydrochloric Acid SCHEMBL5463434 | 0.84 | CDK4 (0.43) | CYP1A1CYP1A2CYP1B1CDK4CCND1 | |
| SCHEMBL6367505 | 0.83 | CYP1B1 (0.77) | CYP1A1CYP1A2CYP1B1CDK4CCND1 | |
| SCHEMBL4901462 | 0.83 | CCND3 (0.47) | TYK2MAPK10CDK4CCND1CCND3 | |
| SCHEMBL4899665 | 0.83 | CDK4 (0.42) | CYP1A1CYP1A2CYP1B1CDK4CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080108600-A1 | Polycyclic Pyridines as Potassium Ion Channel Modulators | ICAGEN, INC. (US) | 2008-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080108600-A1 | Polycyclic Pyridines as Potassium Ion Channel Modulators | KCNJ2, KCNH2, KCNQ1 | CYP1A1 2689/4885CYP1A2 2682/4885CYP1B1 3572/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.