Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK6 | Q00534 | 17/20 | 0.50 |
| ▸ | CCND3 | P30281 | 16/20 | 0.50 |
| ▸ | CDK9 | P50750 | 13/20 | 0.50 |
| ▸ | CCNK | O75909 | 12/20 | 0.50 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.50 |
| ▸ | CDK4 | P11802 | 2/20 | 0.50 |
| ▸ | CCND1 | P24385 | 2/20 | 0.50 |
| ▸ | CDK11A | Q9UQ88 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.46 |
| ▸ | CDK2 | P24941 | 2/20 | 0.46 |
| ▸ | WEE1 | P30291 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CTSC | P53634 | 1/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27682384 | 0.99 | CDK6 (0.49) | CDK6CCND3CDK9CCNKCCNT1 | |
| SCHEMBL4892130 | 0.90 | CCNA2 (0.44) | CDK6CCND3CDK9CCNKCCNT1 | |
| SCHEMBL4893114 | 0.89 | CDK2 (0.45) | CDK6CCND3CDK9CCNKCCNT1 | |
| Hydrochloric Acid SCHEMBL27682318 | 0.88 | CDK2 (0.45) | CDK6CCND3CDK9CCNKCCNT1 | |
| SCHEMBL4902937 | 0.88 | CDK6 (0.49) | CDK6CCND3CDK9CCNKCCNT1 | |
| SCHEMBL4901462 | 0.87 | CCND3 (0.47) | CDK6CCND3CDK9CCNKCDK4 | |
| Hydrochloric Acid SCHEMBL27662847 | 0.86 | CCND3 (0.46) | CDK6CCND3CDK9CCNKCDK4 | |
| Hydrochloric Acid SCHEMBL4900784 | 0.85 | CDK6 (0.45) | CDK6CCND3CDK9CCNKCCNT1 | |
| Hydrochloric Acid SCHEMBL4902390 | 0.85 | CDK6 (0.47) | CDK6CCND3CDK9CCNKCCNT1 | |
| Hydrochloric Acid SCHEMBL5315908 | 0.83 | CDK6 (0.40) | CDK6CCND3CDK9CCNKCCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080108600-A1 | Polycyclic Pyridines as Potassium Ion Channel Modulators | ICAGEN, INC. (US) | 2008-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080108600-A1 | Polycyclic Pyridines as Potassium Ion Channel Modulators | KCNJ2, KCNH2, KCNQ1 | CDK6 2720/4885CCND3 4452/4885CDK9 2935/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.