Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.58 |
| ▸ | BRAF | P15056 | 1/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.58 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.58 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.58 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.58 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.58 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.57 |
| ▸ | ULK1 | O75385 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | PKM | P14618 | 3/20 | 0.51 |
| ▸ | THRB | P10828 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10346126 | 0.88 | KMT2A (0.65) | HDAC1HDAC3BRAFHDAC4HDAC7 | |
| SCHEMBL28308170 | 0.86 | KMT2A (0.51) | HDAC1HDAC3BRAFHDAC4HDAC7 | |
| SCHEMBL1953859 | 0.84 | KMT2A (0.64) | HDAC1HDAC3BRAFHDAC4HDAC7 | |
| SCHEMBL2127722 | 0.83 | PTGS1 (0.77) | HDAC1HDAC3BRAFHDAC4HDAC7 | |
| SCHEMBL6866138 | 0.82 | KMT2A (0.78) | HDAC1HDAC3BRAFHDAC4HDAC7 | |
| SCHEMBL13381189 | 0.82 | MEN1 (0.67) | PTGS1ULK1KMT2AMEN1PKM | |
| SCHEMBL11593046 | 0.82 | PTGS1 (0.75) | HDAC1HDAC2HDAC8HDAC6PTGS1 | |
| SCHEMBL308208 | 0.81 | PTGS1 (0.72) | HDAC1HDAC2HDAC8HDAC6PTGS1 | |
| SCHEMBL2126328 | 0.81 | PTGS1 (0.68) | PTGS1ULK1KMT2AMEN1POLB | |
| SCHEMBL31171978 | 0.81 | PTGS1 (0.72) | HDAC1HDAC2HDAC8HDAC6PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8101731-B2 | Yellow anionic disazo dyes | CIBA SPECIALTY CHEMICALS CORPORATION | 2012-01-24 | — | — | US | disclosed |
| US-8101731-B2 | Yellow anionic disazo dyes | CIBA SPECIALTY CHEMICALS CORPORATION | 2012-01-24 | — | — | US | disclosed |
| US-20100199443-A1 | YELLO ANIONIC DISAZO DYES | LENNARTZ MICHAEL | 2010-08-12 | — | — | US | disclosed |
| US-20100199443-A1 | YELLO ANIONIC DISAZO DYES | LENNARTZ MICHAEL | 2010-08-12 | — | — | US | disclosed |
| US-7723494-B2 | Yellow anionic disazo dyes | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2010-05-25 | — | — | US | disclosed |
| US-7723494-B2 | Yellow anionic disazo dyes | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2010-05-25 | — | — | US | disclosed |
| US-20080119643-A1 | 4,4'-Diazobenzanilide Dyestuffs | LENNARTZ MICHAEL | 2008-05-22 | — | — | US | disclosed |
| US-20080114158-A1 | Yellow anionic disazo dyes | LENNARTZ MICHAEL | 2008-05-15 | — | — | US | disclosed |
| US-20080114158-A1 | Yellow anionic disazo dyes | LENNARTZ MICHAEL | 2008-05-15 | — | — | US | disclosed |
| US-7341607-B2 | Based on diaminobenzanilides or, more specifically (aminobenzoylamino),(sulfo-),(methoxy)anilines; stable aqueous solutions;nonbleeding/colorfastness; excellent degrees of exhaustion with high colour strength; dyeing natural or synthetic materials, particularly, paper; neutral or greenish-yellow hues | CIBA SPECIALTY CHEMICALS CORP. (US) | 2008-03-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080119643-A1 | 4,4'-Diazobenzanilide Dyestuffs | CYP4B1, TYR, DDT | HDAC1 1868/4885HDAC3 872/4885BRAF 1116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.