Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 1/20 | 0.38 |
| ▸ | CCND3 | P30281 | 7/20 | 0.36 |
| ▸ | CDK6 | Q00534 | 7/20 | 0.36 |
| ▸ | CDK4 | P11802 | 6/20 | 0.36 |
| ▸ | CCND1 | P24385 | 6/20 | 0.36 |
| ▸ | CDK9 | P50750 | 5/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.36 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.36 |
| ▸ | CDK7 | P50613 | 1/20 | 0.36 |
| ▸ | CCNH | P51946 | 1/20 | 0.36 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 3/20 | 0.36 |
| ▸ | NTRK2 | Q16620 | 3/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.36 |
| ▸ | CTSC | P53634 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 4/20 | 0.34 |
| ▸ | CDK2 | P24941 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4901103 | 0.91 | CCND3 (0.37) | CCND3CDK6CDK4CCND1CDK9 | |
| SCHEMBL4896616 | 0.89 | HCRTR1 (0.41) | HCRTR1HCRTR2SYKKDM6BCRHR1 | |
| SCHEMBL4899702 | 0.88 | HCRTR1 (0.40) | CCND3CDK6CDK4HCRTR1HCRTR2 | |
| Hydrochloric Acid SCHEMBL5257872 | 0.87 | HCRTR1 (0.40) | CCND3CDK6CDK4HCRTR1HCRTR2 | |
| Hydrochloric Acid SCHEMBL4901700 | 0.86 | PTK2 (0.39) | PTK2CCND3CDK6CDK4CCND1 | |
| Hydrochloric Acid SCHEMBL4892348 | 0.86 | HCRTR1 (0.36) | CCND3CDK6CDK4CCND1HCRTR1 | |
| Hydrochloric Acid SCHEMBL4902615 | 0.85 | MAP4K1 (0.38) | CCND3CDK6CDK4CCND1CDK9 | |
| SCHEMBL4901213 | 0.85 | CTSC (0.47) | CCND3CDK6CDK4CCND1CDK9 | |
| Hydrochloric Acid SCHEMBL4895695 | 0.85 | CDK4 (0.36) | CCND3CDK6CDK4CCND1CDK9 | |
| SCHEMBL4898764 | 0.83 | CDK4 (0.39) | CCND3CDK6CDK4CCND1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080108600-A1 | Polycyclic Pyridines as Potassium Ion Channel Modulators | ICAGEN, INC. (US) | 2008-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080108600-A1 | Polycyclic Pyridines as Potassium Ion Channel Modulators | KCNJ2, KCNH2, KCNQ1 | PTK2 3425/4885CCND3 4452/4885CDK6 2720/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.