Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 10/20 | 0.43 |
| ▸ | CASR | P41180 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4783555 | 0.93 | NR1H2 (0.51) | NR1H2CASRTBXA2REPHX2 | |
| SCHEMBL4913354 | 0.89 | TBXA2R (0.39) | NR1H2CASRTBXA2REPHX2CYP4F2 | |
| SCHEMBL4784456 | 0.86 | NR1H2 (0.42) | NR1H2CASRTBXA2RCYP4F2CYP4A11 | |
| SCHEMBL4784618 | 0.85 | NR1H2 (0.46) | NR1H2CASREPHX2 | |
| SCHEMBL4784213 | 0.83 | NR1H2 (0.42) | NR1H2TBXA2REPHX2 | |
| SCHEMBL4782179 | 0.82 | NR1H2 (0.44) | NR1H2EPHX2 | |
| SCHEMBL4851567 | 0.82 | NR1H2 (0.43) | NR1H2TBXA2R | |
| SCHEMBL4782985 | 0.82 | NR1H2 (0.44) | NR1H2CASREPHX2 | |
| SCHEMBL4784068 | 0.82 | NR1H2 (0.44) | NR1H2EPHX2 | |
| SCHEMBL4785575 | 0.81 | NR1H2 (0.43) | NR1H2CASREPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008061006-A1 | SUBSTITUTED INDAN-2-YL, TETRAHYDRONAPHTHALEN-2-YL, OR DIHYDR0-2H-CHR0MEN-3-YL ARYLSULFONAMIDES AND METHODS OF THEIR USE | WYETH (US) | 2008-05-22 | — | — | WO | disclosed |