SCHEMBL4905282

SCHEMBL4905282

CCCCOCC[N+]1(CC)CCCCC1

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.39
CHRM2 P08172 1/20 0.38
CHRM4 P08173 1/20 0.38
CHRM5 P08912 1/20 0.38
CYP2D6 P10635 1/20 0.38
CHRM1 P11229 1/20 0.38
CHRM3 P20309 1/20 0.38
CYP3A4 P08684 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.33
MEN1 O00255 1/20 0.31
THRB P10828 1/20 0.31
HTT P42858 1/20 0.31
KMT2A Q03164 1/20 0.31
MAPT P10636 1/20 0.31
KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4904905 0.98 TSHR (0.40) TSHRCHRM2CHRM4CHRM5CYP2D6
SCHEMBL17586123 0.90 CHRM2 (0.42) CHRM2CHRM4CHRM5CYP2D6CHRM1
SCHEMBL4903040 0.88 CHRM2 (0.39) CHRM2CHRM4CHRM5CYP2D6CHRM1
SCHEMBL17586134 0.88 CHRM2 (0.41) CHRM2CHRM4CHRM5CYP2D6CHRM1
SCHEMBL17586127 0.88 CHRM2 (0.41) CHRM2CHRM4CHRM5CYP2D6CHRM1
SCHEMBL17586120 0.88 CHRM2 (0.40) CHRM2CHRM4CHRM5CYP2D6CHRM1
SCHEMBL4905009 0.86 CHRM2 (0.37) CHRM2CHRM4CHRM5CYP2D6CHRM1
SCHEMBL17586126 0.86 CHRM2 (0.39) CHRM2CHRM4CHRM5CYP2D6CHRM1
SCHEMBL17581645 0.86 CHRM2 (0.39) CHRM2CHRM4CHRM5CYP2D6CHRM1
SCHEMBL17586129 0.84 KDM4E (0.32) TSHRCHRM2CHRM4CHRM5CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1867667-B1 Method for manufacturing stabilized polyacetal resin POLYPLASTICS CO (JP) 2012-10-31 EP disclosed
US-20080271381-A1 Method for manufacturing stabilized polyacetal resin, stabilized polyacetal resin, stabilized polyacetal resin composition, and molded article of stabilized polyacetal resin POLYPLASTICS CO., LTD (JP) 2008-11-06 US disclosed
EP-1867667-A1 Method for manufacturing stabilized polyacetal resin, stabilized polyacetal resin, stabilized polyacetal resin composition, and molded article of stabilized polyacetal resin Polyplastics Co., Ltd. (JP) 2007-12-19 EP disclosed