Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 8/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ATM | Q13315 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | ALPL | P05186 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24994713 | 0.84 | SCN10A (0.51) | TDP1CHEK1MAPTATMRAB9A | |
| SCHEMBL29488899 | 0.83 | CHEK1 (0.51) | TDP1CHEK1MAPTALDH1A1MEN1 | |
| SCHEMBL24369137 | 0.83 | CHEK1 (0.51) | TDP1CHEK1MAPTALDH1A1MEN1 | |
| SCHEMBL30439099 | 0.81 | CHEK1 (0.50) | CHEK1MAPTMEN1KMT2ARAB9A | |
| SCHEMBL25210972 | 0.81 | CHEK1 (0.50) | CHEK1MAPTMEN1KMT2ARAB9A | |
| SCHEMBL2275652 | 0.81 | TDP1 (0.87) | TDP1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL13019491 | 0.81 | TDP1 (0.87) | TDP1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL16604879 | 0.81 | TDP1 (0.87) | TDP1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL24369756 | 0.80 | CTPS1 (0.49) | CHEK1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL21033709 | 0.79 | TDP1 (0.59) | TDP1MAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080132698-A1 | Use of N-oxide compounds in coupling reactions | UNIVERSITY OF OTTAWA | 2008-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080132698-A1 | Use of N-oxide compounds in coupling reactions | CYP4X1, CYP4F3, CYP1A2 | TDP1 4048/4885CHEK1 2901/4885MAPT 4072/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.