SCHEMBL4905934

SCHEMBL4905934

C=C(C)C(=O)OC(c1ccccc1)(c1ccccc1)c1ccncc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.39
HDAC6 Q9UBN7 1/20 0.38
KIF11 P52732 2/20 0.38
KMT2A Q03164 2/20 0.37
MEN1 O00255 1/20 0.37
CYP2C19 P33261 2/20 0.35
HIF1A Q16665 2/20 0.35
KCNN4 O15554 1/20 0.35
KDM4C Q9H3R0 1/20 0.35
ALDH1A1 P00352 2/20 0.34
KDM4E B2RXH2 2/20 0.34
CYP1A2 P05177 2/20 0.34
CYP2D6 P10635 2/20 0.34
TAAR1 Q96RJ0 1/20 0.34
PLOD2 O00469 1/20 0.34
PLOD3 O60568 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2C9 P11712 1/20 0.34
HPGD P15428 1/20 0.34
PLOD1 Q02809 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10958637 1.00 ELANE (0.39) ELANEHDAC6KIF11KMT2AMEN1
SCHEMBL10793742 1.00 ELANE (0.39) ELANEHDAC6KIF11KMT2AMEN1
SCHEMBL10793049 0.94 CYP19A1 (0.37) ELANEHDAC6CYP2C19ALDH1A1KDM4E
SCHEMBL435821 0.90 ELANE (0.45) ELANEHDAC6KMT2AMEN1CYP2C19
Bicarbonate SCHEMBL27420408 0.89 ELANE (0.44) ELANEHDAC6KMT2AMEN1CYP2C19
Acetic Acid SCHEMBL28277118 0.89 ELANE (0.44) ELANEHDAC6KMT2AMEN1CYP2C19
Phosphine SCHEMBL27261108 0.89 ELANE (0.44) ELANEHDAC6KMT2AMEN1CYP2C19
SCHEMBL10960135 0.88 KCNN4 (0.40) ELANEHDAC6KIF11KMT2AMEN1
SCHEMBL28845220 0.87 ELANE (0.42) ELANEHDAC6KMT2AMEN1CYP2C19
Methacrylic Acid SCHEMBL27752618 0.87 ELANE (0.42) ELANEHDAC6KMT2AMEN1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080003288-A1 Responsive microgel and methods related thereto SUPRATEK PHARMA INC. (CA) 2008-01-03 US disclosed
US-7204997-B2 Responsive microgel and methods related thereto SUPRATEK PHARMA INC. (CA) 2007-04-17 US disclosed
EP-1478403-A1 RESPONSIVE MICROGEL AND METHODS RELATED THERETO SUPRATEK PHARMA, INC. (CA) 2004-11-24 EP disclosed
US-20030152623-A1 Responsive microgel and methods related thereto SUPRATEK PHARMA INC. (CA) 2003-08-14 US disclosed
WO-2003063909-A1 RESPONSIVE MICROGEL AND METHODS RELATED THERETO SUPRATEK PHARMA INC. (US) 2003-08-07 WO disclosed
US-6491903-B1 NARROW MOLECULAR WEIGHT DISTRIBUTION SHELL-CORE POLYMERS HAVING HYDROPHILIC, CROSSLINKED PERMEABLE SHELLS AND HYDROPHOBIC CORES, USED FOR REDUCING BLOOD CHOLESTEROL AND BILE ACID UPTAKE IN INTERSTINES; DRUG DELIVERY WASHINGTON UNIVERSITY 2002-12-10 US disclosed
US-6383500-B1 Particles comprising amphiphilic copolymers, having a crosslinked shell domain and an interior core domain, useful for pharmaceutical and other applications WASHINGTON UNIVERSITY 2002-05-07 US disclosed
EP-0907666-A1 PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS G.D. Searle & Co. (US) 1999-04-14 EP disclosed
WO-1997049736-A2 PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS G.D. SEARLE AND CO. (US) 1997-12-31 WO disclosed
EP-0089530-B1 POLIMERIZATION PROCESS OF OPTICALLY ACTIVE POLYMER AND CATALYST THEREFOR DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1988-06-29 EP disclosed
EP-0095086-B1 POLYMERIZABLE, OPTICALLY ACTIVE POLYMER AND PROCESS FOR PREPARING POLYMERIZABLE POLYMER DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1986-04-09 EP disclosed
US-4555574-A MAIN UNIT OF POLYMER USEFUL AS SEPARATING AGENT DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1985-11-26 US disclosed
US-4554334-A ANIONIC COMPLEX CATALYST DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1985-11-19 US disclosed
US-4554323-A Polymerizable, optically active polymer and process for preparing polymerizable polymer DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1985-11-19 US disclosed
EP-0068290-B1 OPTICALLY ACTIVE POLYMERS OF METHACRYLATE ESTERS DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1985-01-16 EP disclosed
US-4478953-A COORDINATION, POLYMERIZATION CATALYST CONTAINING A LIGAND; ORGANOMETALLIC COMPOUND AND SECONDARY AMINE DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1984-10-23 US disclosed
US-4473690-A FOR OPTICAL RESOLUTIONS DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1984-09-25 US disclosed
EP-0095086-A1 Polymerizable, optically active polymer and process for preparing polymerizable polymer DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1983-11-30 EP disclosed
EP-0089530-A2 Polimerization process of optically active polymer and catalyst therefor DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1983-09-28 EP disclosed
EP-0068290-A1 Optically active polymers of methacrylate esters DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1983-01-05 EP disclosed