SCHEMBL4906101

SCHEMBL4906101

CCN1C(=O)C(=CC=CC=Cc2ccc(N(C)C)cc2)C(=O)N(CC)C1=S

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 11/20 0.63
METAP1 P53582 2/20 0.51
MAPT P10636 13/20 0.50
MEN1 O00255 6/20 0.50
KMT2A Q03164 6/20 0.50
ALDH1A1 P00352 5/20 0.50
THRB P10828 5/20 0.50
L3MBTL1 Q9Y468 5/20 0.50
HTT P42858 3/20 0.50
HPGD P15428 2/20 0.50
KDM4E B2RXH2 1/20 0.50
POLB P06746 1/20 0.50
MDM2 Q00987 1/20 0.50
KDM4C Q9H3R0 1/20 0.50
SNCA P37840 7/20 0.49
MAPK1 P28482 4/20 0.46
TDP1 Q9NUW8 4/20 0.46
NPC1 O15118 3/20 0.46
RECQL P46063 3/20 0.46
RAB9A P51151 3/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14305633 1.00 APP (0.63) APPMETAP1MAPTMEN1KMT2A
SCHEMBL14712975 0.95 METAP1 (0.56) APPMETAP1MAPTMEN1KMT2A
SCHEMBL14712876 0.80 MAPT (0.59) APPMETAP1MAPTMEN1KMT2A
SCHEMBL14712957 0.79 MAPT (0.57) APPMETAP1MAPTMEN1KMT2A
SCHEMBL14712905 0.79 MAPT (0.57) APPMETAP1MAPTMEN1KMT2A
SCHEMBL14712965 0.79 MAPT (0.64) APPMETAP1MAPTMEN1KMT2A
SCHEMBL9970454 0.78 APP (0.71) APPMETAP1MAPTMEN1KMT2A
SCHEMBL14712877 0.78 MAPT (0.64) APPMETAP1MAPTMEN1KMT2A
SCHEMBL16543009 0.77 MAPT (0.55) APPMAPTMEN1KMT2AALDH1A1
SCHEMBL14712964 0.72 MAPT (0.61) APPMETAP1MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080002329-A1 High Dielectric, Non-Linear Capacitor POHM ARTHUR V 2008-01-03 US disclosed
US-20070206342-A1 High Dielectric, Non-Linear Nano-Capacitor NANO-ELECTROCHEM, INC. 2007-09-06 US disclosed
US-20060291278-A1 Nano-Reflectors for Thin, Flat Display Devices NANO-ELECTROCHEM, INC. (US) 2006-12-28 US disclosed