Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 17/20 | 0.62 |
| ▸ | PGR | P06401 | 2/20 | 0.62 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4901017 | 0.84 | AR (0.56) | ARPGRS1PR1 | |
| SCHEMBL4595719 | 0.82 | AR (0.73) | ARPGRS1PR1 | |
| SCHEMBL4595721 | 0.82 | AR (0.73) | ARPGRS1PR1 | |
| SCHEMBL4909107 | 0.81 | AR (0.71) | ARPGRS1PR1 | |
| SCHEMBL3291870 | 0.80 | AR (0.74) | ARPGRS1PR1 | |
| SCHEMBL3291867 | 0.80 | AR (0.74) | ARPGRS1PR1 | |
| SCHEMBL4594825 | 0.79 | AR (0.74) | ARPGRS1PR1 | |
| SCHEMBL14086490 | 0.79 | AR (0.74) | ARPGRS1PR1 | |
| SCHEMBL4596262 | 0.78 | AR (0.81) | ARPGRS1PR1 | |
| SCHEMBL4596266 | 0.78 | AR (0.81) | ARPGRS1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080194536-A1 | Cyanoarylamines | SMITHKLINE BEECHAM CORPORATION | 2008-08-14 | — | — | US | claimed |
| US-20080194536-A1 | Cyanoarylamines | SMITHKLINE BEECHAM CORPORATION | 2008-08-14 | — | — | US | disclosed |
| US-20080194536-A1 | Cyanoarylamines | SMITHKLINE BEECHAM CORPORATION | 2008-08-14 | — | — | US | disclosed |
| US-20080194536-A1 | Cyanoarylamines | SMITHKLINE BEECHAM CORPORATION | 2008-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194536-A1 | Cyanoarylamines | EDNRA, CYP19A1, HSD17B11 | AR 84/4885PGR 64/4885S1PR1 1327/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.