Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | LSS | P48449 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4905120 | 1.00 | EPHX1 (0.47) | EPHX1CYP1A2ALDH1A1MEN1HTT | |
| SCHEMBL2927220 | 1.00 | EPHX1 (0.47) | EPHX1CYP1A2ALDH1A1MEN1HTT | |
| SCHEMBL4906446 | 1.00 | EPHX1 (0.47) | EPHX1CYP1A2ALDH1A1MEN1HTT | |
| SCHEMBL4906247 | 1.00 | EPHX1 (0.47) | EPHX1CYP1A2ALDH1A1MEN1HTT | |
| SCHEMBL4910497 | 0.98 | CYP1A2 (0.48) | EPHX1CYP1A2ALDH1A1MEN1HTT | |
| SCHEMBL17308764 | 0.92 | CYP1A2 (0.56) | EPHX1CYP1A2ALDH1A1MEN1HTT | |
| SCHEMBL14864952 | 0.92 | CYP1A2 (0.56) | EPHX1CYP1A2ALDH1A1MEN1HTT | |
| SCHEMBL3987478 | 0.88 | CYP1A2 (0.50) | EPHX1CYP1A2ALDH1A1MEN1HTT | |
| SCHEMBL14040310 | 0.88 | CYP1A2 (0.50) | EPHX1CYP1A2ALDH1A1MEN1HTT | |
| SCHEMBL11691182 | 0.86 | CYP1A2 (0.59) | EPHX1CYP1A2ALDH1A1MEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8440608-B2 | Beta-substituted tetrandropyrana (on) s and method for the synthesis and the use thereof | V. MANE FILS (FR) | 2013-05-14 | — | — | US | disclosed |
| US-20080032914-A1 | Beta-Substituted Tetrahdropyrana (On) S And Method For The Synthesis And The Use Thereof | V. MANE FILS (FR) | 2008-02-07 | — | — | US | disclosed |