SCHEMBL490919

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL490782	0.88	AAK1 (0.50)	CACNA1BKLK7AAK1USP30PRMT5
	SCHEMBL490591	0.88	AAK1 (0.50)	CACNA1BKLK7AAK1USP30PRMT5
	SCHEMBL490842	0.88	CACNA1B (0.49)	CACNA1BAAK1CTSS
	SCHEMBL490706	0.85	AAK1 (0.49)	CACNA1BKLK7KLK5AAK1USP30
	SCHEMBL490630	0.85	AAK1 (0.49)	CACNA1BKLK7KLK5AAK1USP30
	SCHEMBL10052889	0.84	CACNA1B (0.68)	CACNA1BKLK7KLK5PPARAAAK1
	SCHEMBL490851	0.83	AAK1 (0.46)	CACNA1BKLK7KLK5AAK1USP30
	SCHEMBL490686	0.82	AAK1 (0.55)	CACNA1BKLK7KLK5PPARAAAK1
	SCHEMBL1147671	0.82	CACNA1B (0.47)	CACNA1BKLK7KLK5AAK1USP30
	SCHEMBL490465	0.81	CACNA1B (0.41)	CACNA1BKLK7KLK5AAK1USP30

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.