Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 13/20 | 0.73 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.45 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.45 |
| ▸ | BCHE | P06276 | 4/20 | 0.45 |
| ▸ | ACHE | P22303 | 4/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | THPO | P40225 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4919388 | 1.00 | CHRM2 (0.73) | CHRM2TAAR1SCN8ACA12CA2 | |
| SCHEMBL4908322 | 1.00 | CHRM2 (0.73) | CHRM2TAAR1SCN8ACA12CA2 | |
| SCHEMBL4917141 | 0.96 | CHRM2 (0.72) | CHRM2TAAR1SCN8ACA12CA2 | |
| SCHEMBL4912089 | 0.90 | CHRM2 (0.81) | CHRM2CA12CA2HTTGRIN1 | |
| SCHEMBL4916612 | 0.90 | CHRM2 (0.81) | CHRM2CA12CA2HTTGRIN1 | |
| SCHEMBL5034679 | 0.90 | CHRM2 (0.81) | CHRM2CA12CA2HTTGRIN1 | |
| SCHEMBL14399064 | 0.89 | CHRM2 (0.73) | CHRM2TAAR1SCN8ACA12CA2 | |
| SCHEMBL4913105 | 0.88 | CHRM2 (0.77) | CHRM2TAAR1SCN8ACA12CA2 | |
| SCHEMBL18575559 | 0.82 | CA12 (0.54) | CHRM2CA12CA2GRIN1GRIN2A | |
| SCHEMBL11228760 | 0.81 | CHRM2 (0.53) | CHRM2TAAR1SCN8ACA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1914254-B1 | Crosslinkers for improving stability of polyurethane foams | EVONIK DEGUSSA GMBH (DE) | 2017-08-23 | — | — | EP | disclosed |
| US-8552078-B2 | Non-fugitive tertiary amine catalyst and alkylated polyamine crosslinking additives; aging resistance | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2013-10-08 | — | — | US | disclosed |
| CN-101168601-A | Crosslinkers for improving stability of polyurethane foams | AIR PROD & CHEM (US) | 2008-04-30 | — | — | CN | disclosed |
| EP-1914254-A1 | Crosslinkers for improving stability of polyurethane foams | Air Products and Chemicals, Inc. (US) | 2008-04-23 | — | — | EP | disclosed |
| US-20080090922-A1 | Crosslinkers for improving stability of polyurethane foams | EVONIK OPERATIONS GMBH (DE) | 2008-04-17 | — | — | US | disclosed |