SCHEMBL491018

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL490601	0.91	CACNA1B (0.43)	CACNA1BAAK1KLK7KDM4EALDH1A1
	SCHEMBL490782	0.88	AAK1 (0.50)	CACNA1BAAK1KLK7HRH2HRH1
	SCHEMBL490591	0.88	AAK1 (0.50)	CACNA1BAAK1KLK7HRH2HRH1
	SCHEMBL1147671	0.86	CACNA1B (0.47)	CACNA1BAAK1KLK7ITGB3ITGA2B
	SCHEMBL490851	0.84	AAK1 (0.46)	CACNA1BAAK1KLK7KDM4EALDH1A1
	SCHEMBL490630	0.83	AAK1 (0.49)	CACNA1BAAK1KLK7HRH2HRH1
	SCHEMBL490706	0.83	AAK1 (0.49)	CACNA1BAAK1KLK7HRH2HRH1
	SCHEMBL490686	0.80	AAK1 (0.55)	CACNA1BAAK1KLK7KDM4EALDH1A1
	SCHEMBL13421977	0.78	CACNA1B (0.49)	CACNA1BKLK7ALDH1A1HRH2HRH1
	SCHEMBL8257659	0.78	CACNA1B (0.51)	CACNA1BAAK1KLK7HRH2HRH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.