Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CTSD | P07339 | 2/20 | 0.39 |
| ▸ | CTSL | P07711 | 2/20 | 0.39 |
| ▸ | CTSB | P07858 | 2/20 | 0.39 |
| ▸ | CTSS | P25774 | 2/20 | 0.39 |
| ▸ | DPP4 | P27487 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8426486 | 1.00 | RECQL (0.53) | RECQLUSP2SMN1; SMN2HSD17B10CTSD | |
| SCHEMBL13462046 | 0.89 | HPGD (0.49) | RECQLHSD17B10DPP4HPGDMEN1 | |
| SCHEMBL4922712 | 0.89 | HPGD (0.49) | RECQLHSD17B10DPP4HPGDMEN1 | |
| SCHEMBL8426484 | 0.83 | RECQL (0.54) | RECQLUSP2SMN1; SMN2HSD17B10HPGD | |
| SCHEMBL13567876 | 0.83 | RECQL (0.54) | RECQLUSP2SMN1; SMN2HSD17B10HPGD | |
| SCHEMBL8272250 | 0.83 | RECQL (0.54) | RECQLUSP2SMN1; SMN2HSD17B10HPGD | |
| SCHEMBL13567832 | 0.83 | RECQL (0.54) | RECQLUSP2SMN1; SMN2HSD17B10HPGD | |
| SCHEMBL8426465 | 0.82 | HSD17B10 (0.43) | RECQLHSD17B10DPP4HPGDMEN1 | |
| SCHEMBL13567875 | 0.81 | RECQL (0.53) | RECQLUSP2SMN1; SMN2HSD17B10DPP4 | |
| SCHEMBL13567830 | 0.81 | RECQL (0.53) | RECQLUSP2SMN1; SMN2HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080119464-A1 | PHARMACEUTICAL COMPOSITIONS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE-IV (DPP-IV) | ABBVIE INC. | 2008-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080119464-A1 | PHARMACEUTICAL COMPOSITIONS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE-IV (DPP-IV) | DPP4, DPP3, DPP7 | RECQL 2381/4885USP2 1791/4885SMN1; SMN2 4790/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.