Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NISCH | Q9Y2I1 | 5/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4362117 | 0.94 | SMN1; SMN2 (0.40) | SMN1; SMN2NLRP3KMT2ANISCHNPC1 | |
| Formic Acid SCHEMBL4911283 | 0.83 | NISCH (0.43) | SMN1; SMN2KMT2ANISCHMAPT | |
| SCHEMBL4158125 | 0.78 | NISCH (0.53) | SMN1; SMN2NLRP3KMT2ANISCHMAPK1 | |
| SCHEMBL4362412 | 0.78 | NISCH (0.45) | SMN1; SMN2NLRP3KMT2ANISCHNPC1 | |
| Hydrochloric Acid SCHEMBL4907535 | 0.77 | NISCH (0.44) | SMN1; SMN2NLRP3KMT2ANISCHNPC1 | |
| SCHEMBL4360959 | 0.76 | NISCH (0.47) | SMN1; SMN2KMT2ANISCHNPC1RAB9A | |
| SCHEMBL4152820 | 0.76 | NISCH (0.45) | SMN1; SMN2NLRP3KMT2ANISCHNPC1 | |
| Hydrochloric Acid SCHEMBL4910391 | 0.75 | NISCH (0.44) | SMN1; SMN2NLRP3KMT2ANISCHNPC1 | |
| Formic Acid SCHEMBL4911286 | 0.74 | NISCH (0.37) | NISCHADRA2AADRA2BADRA2CGAA | |
| Formic Acid SCHEMBL4912608 | 0.74 | NISCH (0.51) | NISCHMAPK1TAAR1LMNAHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080269217-A1 | Melanocortin-4 receptor binding compounds and methods of use thereof | ORE PHARMACEUTICALS, INC. (US) | 2008-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269217-A1 | Melanocortin-4 receptor binding compounds and methods of use thereof | MC4R, MC5R, MC3R | SMN1; SMN2 3087/4885NLRP3 3694/4885KMT2A 1838/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.