Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 13/20 | 1.00 |
| ▸ | ADORA2A | P29274 | 12/20 | 1.00 |
| ▸ | MEN1 | O00255 | 3/20 | 0.83 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.83 |
| ▸ | PIM1 | P11309 | 1/20 | 0.83 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.83 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.76 |
| ▸ | GLA | P06280 | 1/20 | 0.76 |
| ▸ | GAA | P10253 | 1/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.71 |
| ▸ | HPGD | P15428 | 2/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.71 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.69 |
| ▸ | MAPT | P10636 | 1/20 | 0.68 |
| ▸ | TSHR | P16473 | 1/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31120336 | 1.00 | ADORA1 (1.00) | ADORA1ADORA2AMEN1KMT2APIM1 | |
| SCHEMBL31120344 | 0.92 | ADORA1 (0.85) | ADORA1ADORA2AMEN1KMT2APIM1 | |
| SCHEMBL31120351 | 0.91 | ADORA1 (0.83) | ADORA1ADORA2AMEN1KMT2APIM1 | |
| SCHEMBL31120420 | 0.91 | ADORA1 (1.00) | ADORA1ADORA2AMEN1KMT2APIM1 | |
| SCHEMBL31120383 | 0.91 | ADORA1 (1.00) | ADORA1ADORA2AMEN1KMT2APIM1 | |
| SCHEMBL31120396 | 0.91 | ADORA1 (1.00) | ADORA1ADORA2AMEN1KMT2APIM1 | |
| SCHEMBL22215854 | 0.91 | ADORA1 (1.00) | ADORA1ADORA2AMEN1KMT2APIM1 | |
| SCHEMBL22215734 | 0.91 | ADORA1 (1.00) | ADORA1ADORA2AMEN1KMT2APIM1 | |
| SCHEMBL22208383 | 0.91 | ADORA1 (1.00) | ADORA1ADORA2AMEN1KMT2APIM1 | |
| SCHEMBL31120337 | 0.91 | ADORA1 (1.00) | ADORA1ADORA2AMEN1KMT2APIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150027928-A1 | Ionic liquids, methylcarbonate- or carboxylates-based, obtaining process and use thereof | INSTITUTO MEXICANO DEL PETROLEO (MX) | 2015-01-29 | — | — | US | disclosed |
| US-20080139608-A1 | 2,6,8, Trisubstituted 1-deazapurines and their different uses | UNIVERSITEIT LEIDEN (NL) | 2008-06-12 | — | — | US | disclosed |
| US-20080139608-A1 | 2,6,8, Trisubstituted 1-deazapurines and their different uses | UNIVERSITEIT LEIDEN (NL) | 2008-06-12 | — | — | US | disclosed |
| US-20080139608-A1 | 2,6,8, Trisubstituted 1-deazapurines and their different uses | UNIVERSITEIT LEIDEN (NL) | 2008-06-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080139608-A1 | 2,6,8, Trisubstituted 1-deazapurines and their different uses | TPMT, NAT1, MTAP | ADORA1 204/4885ADORA2A 142/4885MEN1 3183/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.