Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | ANPEP | P15144 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | ALPI | P09923 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | XIAP | P98170 | 1/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4557627 | 1.00 | TAAR1 (0.53) | TAAR1SLC6A2SLC6A4SLC6A3EPHX1 | |
| SCHEMBL9191396 | 0.82 | HRH1 (0.53) | TAAR1SLC6A2SLC6A4SLC6A3EPHX1 | |
| SCHEMBL10913591 | 0.80 | HTR2A (0.57) | TAAR1SLC6A2SLC6A4SLC6A3EPHX1 | |
| SCHEMBL24017042 | 0.78 | EPHX1 (0.70) | TAAR1SLC6A2SLC6A4SLC6A3EPHX1 | |
| SCHEMBL9536448 | 0.78 | EPHX1 (0.70) | TAAR1SLC6A2SLC6A4SLC6A3EPHX1 | |
| SCHEMBL8995001 | 0.78 | TAAR1 (0.73) | TAAR1SLC6A2SLC6A4SLC6A3HTR2A | |
| SCHEMBL1169184 | 0.77 | TACR1 (0.58) | TAAR1SLC6A2SLC6A4SLC6A3EPHX1 | |
| SCHEMBL5872302 | 0.77 | TACR1 (0.58) | TAAR1SLC6A2SLC6A4SLC6A3EPHX1 | |
| SCHEMBL4978886 | 0.77 | DPP4 (0.56) | TAAR1SLC6A2SLC6A4SLC6A3EPHX1 | |
| SCHEMBL8761504 | 0.75 | EPHX1 (0.52) | TAAR1SLC6A2SLC6A4SLC6A3EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017033134-A1 | ENZYMATIC PROCESS FOR THE FOR PREPARATION OF (R)-1-(1-NAPHTHYL) ETHYLAMINE, AN INTERMEDIATE OF CINACALCET HYDROCHLORIDE | LUPIN LIMITED (IN) | 2017-03-02 | — | — | WO | claimed |
| US-20080021042-A1 | Composition For Controlling Neuropathic Pain | MARUISHI PHARMACEUTICAL CO., LTD. (JP) | 2008-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080021042-A1 | Composition For Controlling Neuropathic Pain | GAP43, SCN10A, SCN2A | TAAR1 1321/4885SLC6A2 182/4885SLC6A4 380/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.