Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 12/20 | 0.77 |
| ▸ | HDAC6 | Q9UBN7 | 12/20 | 0.77 |
| ▸ | HDAC3 | O15379 | 11/20 | 0.77 |
| ▸ | HDAC4 | P56524 | 11/20 | 0.77 |
| ▸ | HDAC7 | Q8WUI4 | 11/20 | 0.77 |
| ▸ | HDAC2 | Q92769 | 11/20 | 0.77 |
| ▸ | HDAC10 | Q969S8 | 11/20 | 0.77 |
| ▸ | HDAC11 | Q96DB2 | 11/20 | 0.77 |
| ▸ | HDAC8 | Q9BY41 | 11/20 | 0.77 |
| ▸ | HDAC9 | Q9UKV0 | 11/20 | 0.77 |
| ▸ | HDAC5 | Q9UQL6 | 11/20 | 0.77 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | FAAH | O00519 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4929026 | 0.88 | HDAC1 (0.77) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL4926584 | 0.88 | HDAC3 (0.77) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL4926485 | 0.87 | HDAC3 (0.79) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL4916650 | 0.87 | HDAC1 (0.72) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL4926463 | 0.87 | HDAC3 (1.00) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL4925628 | 0.87 | HDAC1 (0.82) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL5174817 | 0.83 | HDAC1 (0.61) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL4927435 | 0.83 | HDAC3 (0.76) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL4923890 | 0.81 | HDAC1 (0.72) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL4930468 | 0.81 | HDAC3 (0.54) | HDAC1HDAC6HDAC3HDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080207694-A1 | Hydroxamates as Histone Deacetylase Inhibitors and Pharmaceutical Formulations Containing Them | ROSSI CRISTINA | 2008-08-28 | — | — | US | claimed |
| US-20080207694-A1 | Hydroxamates as Histone Deacetylase Inhibitors and Pharmaceutical Formulations Containing Them | ROSSI CRISTINA | 2008-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080207694-A1 | Hydroxamates as Histone Deacetylase Inhibitors and Pharmaceutical Formulations Containing Them | HDAC1, HDAC8, HDAC9 | HDAC1 1/4885HDAC6 11/4885HDAC3 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.