Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | DNM1 | Q05193 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3016529 | 1.00 | TSHR (0.53) | TSHRTHRBDNM1ALDH1A1LMNA | |
| SCHEMBL28175581 | 1.00 | TSHR (0.53) | TSHRTHRBDNM1ALDH1A1LMNA | |
| SCHEMBL27895831 | 1.00 | TSHR (0.53) | TSHRTHRBDNM1ALDH1A1LMNA | |
| SCHEMBL9666319 | 1.00 | TSHR (0.53) | TSHRTHRBDNM1ALDH1A1LMNA | |
| SCHEMBL17629227 | 1.00 | TSHR (0.53) | TSHRTHRBDNM1ALDH1A1LMNA | |
| SCHEMBL1695965 | 1.00 | TSHR (0.53) | TSHRTHRBDNM1ALDH1A1LMNA | |
| SCHEMBL6169218 | 1.00 | TSHR (0.53) | TSHRTHRBDNM1ALDH1A1LMNA | |
| SCHEMBL7515018 | 1.00 | TSHR (0.53) | TSHRTHRBDNM1ALDH1A1LMNA | |
| SCHEMBL561270 | 1.00 | TSHR (0.53) | TSHRTHRBDNM1ALDH1A1LMNA | |
| SCHEMBL6303860 | 1.00 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10100199-B2 | Methylsilyl derivatised silica particles, colloids, methods for manufacture and kits comprising the same | AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) | 2018-10-16 | — | — | US | disclosed |
| US-20180044531-A1 | METHYLSILYL DERIVATISED SILICA PARTICLES, COLLOIDS, METHODS FOR MANUFACTURE AND KITS COMPRISING THE SAME | WILMINGTON TRUST (LONDON) LIMITED, AS COLLATERAL AGENT (GB) | 2018-02-15 | — | — | US | disclosed |
| EP-3268436-A1 | METHYLSILYL DERIVATISED SILICA PARTICLES, COLLOIDS, METHODS FOR MANUFACTURE AND KITS COMPRISING THE SAME | Akzo Nobel Chemicals International B.V. (NL) | 2018-01-17 | — | — | EP | disclosed |
| WO-2016142404-A1 | METHYLSILYL DERIVATISED SILICA PARTICLES, COLLOIDS, METHODS FOR MANUFACTURE AND KITS COMPRISING THE SAME | AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) | 2016-09-15 | — | — | WO | disclosed |
| US-8084520-B2 | Epoxy resin composition and semiconductor device | SUMITOMO BAKELITE CO., LTD. (JP) | 2011-12-27 | — | — | US | disclosed |
| US-20080064791-A1 | Encapsulation; reliable high temperature operation; including phenol resin, curing accelerator, silica and alumina | SUMITOMO BAKELITE CO., LTD. (JP) | 2008-03-13 | — | — | US | disclosed |
| US-6072085-A | COMBINING SUBSTRATE IMINE, NUCLEOPHILIC ACTIVATOR, SILANE, METAL CATALYST, WHEREIN CATALYST CATALYZES REDUCTION OF IMINE BY HYDROSILATION | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2000-06-06 | — | — | US | disclosed |
| EP-0630933-B1 | A method of producing a semiconducting material | NIPPON OIL CO LTD (JP) | 1999-04-14 | — | — | EP | disclosed |
| US-5700400-A | Method for producing a semiconducting material | NIPPON OIL CO., LTD. (JP) | 1997-12-23 | — | — | US | disclosed |
| EP-0551771-B1 | Process for producing polysilanes | NIPPON OIL CO LTD (JP) | 1997-07-30 | — | — | EP | disclosed |
| US-5620531-A | Photovoltaic element | NIPPON OIL CO., LTD. (JP) | 1997-04-15 | — | — | US | disclosed |
| EP-0717451-A2 | Photovoltaic element | NIPPON OIL CO., LTD. (JP) | 1996-06-19 | — | — | EP | disclosed |
| EP-0630933-A2 | A method of producing a semiconducting material | NIPPON OIL CO. LTD. (JP) | 1994-12-28 | — | — | EP | disclosed |
| US-5304622-A | Process for producing polysilanes | NIPPON OIL COMPANY, LTD. (JP) | 1994-04-19 | — | — | US | disclosed |
| EP-0551771-A2 | Process for producing polysilanes | NIPPON OIL CO. LTD. (JP) | 1993-07-21 | — | — | EP | disclosed |