Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCNN1A | P37088 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | GLA | P06280 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | PLAU | P00749 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | SLC9A5 | Q14940 | 2/20 | 0.34 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1928765 | 0.89 | SCNN1A (0.40) | SCNN1AKDM4EALDH1A1GLAHPGD | |
| Bromide SCHEMBL4693421 | 0.84 | SCNN1A (0.44) | SCNN1AKDM4EALDH1A1GLAHPGD | |
| Hydrochloric Acid SCHEMBL4693835 | 0.83 | KDM4E (0.46) | SCNN1AKDM4EALDH1A1GLAHPGD | |
| Bromide SCHEMBL4789642 | 0.83 | SCNN1A (0.43) | SCNN1AKDM4EALDH1A1GLAHPGD | |
| SCHEMBL1930542 | 0.82 | SCNN1A (0.39) | SCNN1AKDM4EALDH1A1GLAHPGD | |
| Hydrochloric Acid SCHEMBL5035664 | 0.81 | SLC9A5 (0.33) | SCNN1AKDM4EALDH1A1GLAHPGD | |
| SCHEMBL1930898 | 0.80 | KDM4E (0.32) | SCNN1AKDM4EALDH1A1GLAHPGD | |
| SCHEMBL1930588 | 0.80 | KDM4E (0.32) | SCNN1AKDM4EALDH1A1GLAHPGD | |
| SCHEMBL6013440 | 0.79 | SCNN1A (0.40) | SCNN1AKDM4EALDH1A1GLAHPGD | |
| SCHEMBL4418118 | 0.79 | SCNN1A (0.40) | SCNN1AKDM4EALDH1A1GLAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080096896-A1 | Cyclic Amide & Ester Pyrazinoylganidine Sodium Channel Blockers | PARION SCIENCES, INC. (US) | 2008-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080096896-A1 | Cyclic Amide & Ester Pyrazinoylganidine Sodium Channel Blockers | HCN4, CACNA1B, SCN5A | SCNN1A 13/4885KDM4E 2052/4885ALDH1A1 1549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.