Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 20/20 | 0.60 |
| ▸ | CHUK | O15111 | 4/20 | 0.55 |
| ▸ | EPHA3 | P29320 | 3/20 | 0.55 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.55 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4914374 | 0.94 | IKBKB (0.70) | IKBKBCHUKEPHA3NTRK1PDGFRA | |
| SCHEMBL4918938 | 0.91 | IKBKB (0.64) | IKBKBCHUKEPHA3NTRK1PDGFRA | |
| SCHEMBL4922403 | 0.85 | IKBKB (0.61) | IKBKBCHUKEPHA3NTRK1PDGFRA | |
| SCHEMBL4918303 | 0.84 | IKBKB (0.74) | IKBKBCHUKEPHA3NTRK1PDGFRA | |
| SCHEMBL6278515 | 0.81 | IKBKB (0.74) | IKBKBCHUKEPHA3NTRK1PDGFRA | |
| SCHEMBL4918219 | 0.80 | IKBKB (0.67) | IKBKBCHUKEPHA3NTRK1PDGFRA | |
| SCHEMBL6427692 | 0.80 | IKBKB (0.71) | IKBKBCHUKEPHA3NTRK1PDGFRA | |
| SCHEMBL4920160 | 0.79 | IKBKB (0.71) | IKBKBCHUKEPHA3NTRK1PDGFRA | |
| SCHEMBL4657625 | 0.79 | IKBKB (0.81) | IKBKBCHUKEPHA3NTRK1PDGFRA | |
| SCHEMBL4916294 | 0.79 | IKBKB (0.58) | IKBKBCHUKEPHA3NTRK1PDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080312185-A1 | SUBSTITUTED 3-AMINO-THIENO[2,3-b]PYRIDINE-2-CARBOXYLIC ACID AMIDE COMPOUNDS AND PROCESSES FOR PREPARING AND THEIR USES | CHEN ZHIDONG | 2008-12-18 | — | — | US | disclosed |
| US-7119102-B2 | Substituted 3-amino-thieno[2,3-b]pyridine-2-carboxylic acid amide compounds and processes for preparing and their uses | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2006-10-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312185-A1 | SUBSTITUTED 3-AMINO-THIENO[2,3-b]PYRIDINE-2-CARBOXYLIC ACID AMIDE COMPOUNDS AND PROCESSES FOR PREPARING AND THEIR USES | CPS1, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, TK2 | IKBKB 1060/4885CHUK 427/4885EPHA3 3431/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.