SCHEMBL491992

SCHEMBL491992

SC1COCC[N]1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1337870 0.67
SCHEMBL1609639 0.67
SCHEMBL2043577 0.67
SCHEMBL1609662 0.67
SCHEMBL2044354 0.67
SCHEMBL4575 0.67
SCHEMBL3945631 0.63
SCHEMBL4465131 0.63
SCHEMBL1609131 0.62
SCHEMBL4477943 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 279 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108948002-A Five yuan and hexa-atomic nitrogen heteroaromatic rings class compound, preparation method, Pharmaceutical composition and its application 厦门大学 2018-12-07 CN claimed
CN-107151250-A Miazines compounds with 7-member cycle, its preparation method, Pharmaceutical composition and its application 安徽省新星药物开发有限责任公司 2017-09-12 CN claimed
CN-1671639-A Novel biphenyl and biphenyl-like cannabinoids UNIV CONNECTICUT (US) 2005-09-21 CN claimed
CN-110461854-A Process for preparing chiral 2, 3-dihydrothiazolo [3,2-A ] pyrimidin-4-ium compounds BASF SE 2019-11-15 CN disclosed
CN-107223125-B SGC stimulant 赛科理音医疗有限公司 2019-09-27 CN disclosed
CN-109311789-A The method for preparing 2,3- unsaturated alcohol 巴斯夫欧洲公司 2019-02-05 CN disclosed
CN-109134451-A 1,3- 2-substituted carbamide class and thiourea derivatives and its application 遵义医学院 2019-01-04 CN disclosed
CN-108948002-A Five yuan and hexa-atomic nitrogen heteroaromatic rings class compound, preparation method, Pharmaceutical composition and its application 厦门大学 2018-12-07 CN disclosed
CN-107151250-A Miazines compounds with 7-member cycle, its preparation method, Pharmaceutical composition and its application 安徽省新星药物开发有限责任公司 2017-09-12 CN disclosed
CN-104662008-B Deprotection method of tetrazole compound 株式会社API 2017-03-08 CN disclosed
CN-106304835-A Sgc stimulant 铁木医药有限公司 2017-01-04 CN disclosed
CN-1026489-C Antirhinoviral (thio) morpholinyl and piperazinyl alkylphenol ethers JANSSEN PHARMACEUTICA NV (BE) 1994-11-09 CN disclosed
EP-0398426-B1 Antirhinoviral (thio)morpholinyl and piperazinyl alkylphenol ethers JANSSEN PHARMACEUTICA NV (BE) 1994-03-09 EP disclosed
EP-0398426-B1 Antirhinoviral (thio)morpholinyl and piperazinyl alkylphenol ethers JANSSEN PHARMACEUTICA NV (BE) 1994-03-09 EP disclosed
CN-1068333-A Has hydrazine analog derivative of pharmacologically active and preparation method thereof CIBA GEIGY AG (CH) 1993-01-27 CN disclosed
US-5070090-A SUSTAINED RELEASE FROM CYCLODEXTRIN INCLUSION COMPOUND JANSSEN PHARMACEUTICA N.V. (BE) 1991-12-03 US disclosed
US-5070090-A SUSTAINED RELEASE FROM CYCLODEXTRIN INCLUSION COMPOUND JANSSEN PHARMACEUTICA N.V. (BE) 1991-12-03 US disclosed
EP-0398426-A1 Antirhinoviral (thio)morpholinyl and piperazinyl alkylphenol ethers JANSSEN PHARMACEUTICA N.V. (BE) 1990-11-22 EP disclosed
EP-0398426-A1 Antirhinoviral (thio)morpholinyl and piperazinyl alkylphenol ethers JANSSEN PHARMACEUTICA N.V. (BE) 1990-11-22 EP disclosed
EP-0398426-A1 Antirhinoviral (thio)morpholinyl and piperazinyl alkylphenol ethers JANSSEN PHARMACEUTICA N.V. (BE) 1990-11-22 EP disclosed