Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 18/20 | 0.65 |
| ▸ | ESR2 | Q92731 | 18/20 | 0.65 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.51 |
| ▸ | STS | P08842 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14070512 | 0.95 | ESR1 (0.67) | ESR1ESR2ABCC1STS | |
| SCHEMBL4924099 | 0.89 | ESR1 (0.55) | ESR1ESR2STS | |
| SCHEMBL4920629 | 0.86 | ESR1 (0.66) | ESR1ESR2ABCC1STS | |
| SCHEMBL4924889 | 0.85 | ESR1 (0.54) | ESR1ESR2 | |
| SCHEMBL5424599 | 0.85 | ESR1 (0.61) | ESR1ESR2 | |
| SCHEMBL14070522 | 0.84 | ESR1 (0.57) | ESR1ESR2STS | |
| SCHEMBL8472971 | 0.84 | ESR1 (0.71) | ESR1ESR2 | |
| Hydrochloric Acid SCHEMBL3116478 | 0.82 | ESR1 (0.76) | ESR1ESR2ABCC1 | |
| SCHEMBL14070511 | 0.81 | ESR1 (0.52) | ESR1ESR2 | |
| SCHEMBL8477101 | 0.81 | ESR1 (0.62) | ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080221163-A1 | Selective Estrogen Receptor Modulators | ELI LILLY AND COMPANY | 2008-09-11 | — | — | US | disclosed |
| EP-1713820-A1 | SELECTIVE ESTROGEN RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2006-10-25 | — | — | EP | disclosed |
| WO-2005073244-A1 | SELECTIVE ESTROGEN RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-08-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221163-A1 | Selective Estrogen Receptor Modulators | GPER1, ESR2, ESR1 | ESR1 3/4885ESR2 2/4885ABCC1 2190/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.