⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL667583 | 1.00 | — | — | |
| SCHEMBL668058 | 1.00 | — | — | |
| SCHEMBL482779 | 0.84 | — | — | |
| SCHEMBL294554 | 0.82 | — | — | |
| SCHEMBL1855227 | 0.76 | — | — | |
| SCHEMBL1579432 | 0.72 | CARM1 (0.31) | — | |
| SCHEMBL689663 | 0.72 | — | — | |
| SCHEMBL9838432 | 0.72 | — | — | |
| SCHEMBL666686 | 0.72 | — | — | |
| SCHEMBL666631 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 279 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112010844-B | Preparation method and application of N- (pyrimidine-2-yl) coumarin-7-amine derivative as protein kinase inhibitor | 中国药科大学 | 2023-07-25 | — | — | CN | claimed |
| US-20230219973-A1 | DEUBIQUITINASE INHIBITORS AND METHODS OF USE THEREOF | MOLECURE S.A. (PL) | 2023-07-13 | — | — | US | claimed |
| CN-113801108-A | Protein kinase inhibitor and derivative thereof, preparation method, pharmaceutical composition and application | 中国药科大学 | 2021-12-17 | — | — | CN | claimed |
| CN-113549018-A | Protein kinase inhibitor and derivative thereof, preparation method, pharmaceutical composition and application | 中国药科大学 | 2021-10-26 | — | — | CN | claimed |
| CN-112010844-A | Preparation method and application of N- (pyrimidine-2-yl) coumarin-7-amine derivative as protein kinase inhibitor | 中国药科大学 | 2020-12-01 | — | — | CN | claimed |
| US-20190119272-A1 | TRIAZOLOPYRIDINES AND TRIAZOLOPYRAZINES AS LSD1 INHIBITORS | INCYTE CORPORATION | 2019-04-25 | — | — | US | claimed |
| US-10125133-B2 | Substituted [1,2,4]triazolo[1,5-a]pyridines and substituted [1,2,4]triazolo[1,5-a]pyrazines as LSD1 inhibitors | INCYTE CORPORATION (US) | 2018-11-13 | — | — | US | claimed |
| US-20170369488-A1 | TRIAZOLOPYRIDINES AND TRIAZOLOPYRAZINES AS LSD1 INHIBITORS | INCYTE CORPORATION | 2017-12-28 | — | — | US | claimed |
| US-9695167-B2 | Substituted triazolo[1,5-a]pyridines and triazolo[1,5-a]pyrazines as LSD1 inhibitors | INCYTE CORPORATION (US) | 2017-07-04 | — | — | US | claimed |
| WO-2016007722-A1 | TRIAZOLOPYRIDINES AND TRIAZOLOPYRAZINES AS LSD1 INHIBITORS | INCYTE CORPORATION (US) | 2016-01-14 | — | — | WO | claimed |
| WO-2004083207-A1 | NAPHTHYRIDINE DERIVATIVES AS ANTIBACTERIAL AGENTS | ABBOTT LABORATORIES (US) | 2004-09-30 | — | — | WO | claimed |
| US-20030232818-A1 | Antibacterial compounds | ABBVIE INC. | 2003-12-18 | — | — | US | claimed |
| EP-0614664-B2 | Quinolonecarboxylic acid derivatives, their preparation and their use as cell adhesion inhibitors | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-01-08 | — | — | EP | claimed |
| EP-0614664-B1 | Quinolonecarboxylic acid derivatives, their preparation and their use as cell adhesion inhibitors | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1998-09-16 | — | — | EP | claimed |
| EP-0160284-B1 | QUINO-BENOXAZINE ANTIBACTERIAL COMPOUNDS | ABBOTT LABORATORIES (US) | 1990-10-24 | — | — | EP | claimed |
| EP-0162333-B1 | QUINO-BENZOTHIAZINE ANTIBACTERIAL COMPOUNDS | ABBOTT LABORATORIES (US) | 1990-06-27 | — | — | EP | claimed |
| US-4607032-A | Quino-benoxazine antibacterial compounds | ABBOTT LABORATORIES (US) | 1986-08-19 | — | — | US | claimed |
| EP-0162333-A1 | Quino-benzothiazine antibacterial compounds | ABBOTT LABORATORIES (US) | 1985-11-27 | — | — | EP | claimed |
| EP-0160284-A1 | Quino-benoxazine antibacterial compounds | ABBOTT LABORATORIES (US) | 1985-11-06 | — | — | EP | claimed |
| US-4533663-A | Quino-benzothiazine antibacterial compounds | ABBOTT LABORATORIES (US) | 1985-08-06 | — | — | US | claimed |