Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14281186 | 0.94 | F10 (0.55) | F10 | |
| SCHEMBL4912657 | 0.88 | F10 (0.49) | F10 | |
| SCHEMBL12754754 | 0.82 | TDP1 (0.52) | F10 | |
| SCHEMBL1481964 | 0.82 | TDP1 (0.52) | F10 | |
| SCHEMBL4919695 | 0.82 | F10 (0.53) | F10 | |
| SCHEMBL4925760 | 0.81 | EPHX2 (0.44) | AKT1 | |
| SCHEMBL4916531 | 0.80 | F10 (0.52) | F10 | |
| SCHEMBL4920922 | 0.80 | F10 (0.52) | F10 | |
| SCHEMBL28755710 | 0.80 | F10 (0.68) | F10 | |
| SCHEMBL4919080 | 0.79 | F10 (0.51) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080015178-A1 | BENZIMIDAZOLES, PROCESS FOR THEIR PREPARATION AND USE THEREOF AS MEDICAMENT | GERLACH KAI | 2008-01-17 | — | — | US | claimed |
| US-20050272792-A1 | Benzimidazoles, process for their preparation and use thereof as medicament | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-12-08 | — | — | US | claimed |
| US-20080015178-A1 | BENZIMIDAZOLES, PROCESS FOR THEIR PREPARATION AND USE THEREOF AS MEDICAMENT | GERLACH KAI | 2008-01-17 | — | — | US | disclosed |
| US-20050272792-A1 | Benzimidazoles, process for their preparation and use thereof as medicament | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050272792-A1 | Benzimidazoles, process for their preparation and use thereof as medicament | CYP2C19, CYP3A4, CYP2B6 | F10 3212/4885AKT1 3840/4885 |
| US-20080015178-A1 | BENZIMIDAZOLES, PROCESS FOR THEIR PREPARATION AND USE THEREOF AS MEDICAMENT | CYP2C19, CYP3A4, CYP2B6 | F10 3212/4885AKT1 3840/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.