Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAL | P20701 | 1/20 | 0.62 |
| ▸ | ITGB1 | P05556 | 12/20 | 0.36 |
| ▸ | ITGA5 | P08648 | 9/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | APLNR | P35414 | 1/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 4/20 | 0.33 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | ITGAV | P06756 | 3/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.32 |
| ▸ | SPR | P35270 | 1/20 | 0.32 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12054488 | 1.00 | ITGAL (0.62) | ITGALITGB1ITGA5ADRB1ADRB3 | |
| SCHEMBL19157561 | 1.00 | ITGAL (0.62) | ITGALITGB1ITGA5ADRB1ADRB3 | |
| SCHEMBL16307471 | 0.96 | ITGAL (0.57) | ITGALITGB1ITGA5ADRB1ADRB3 | |
| SCHEMBL12169844 | 0.93 | ITGAL (0.63) | ITGALITGB1ITGA5ADRB1ADRB3 | |
| SCHEMBL12415082 | 0.92 | ITGAL (0.63) | ITGALITGB1ITGA5ADRB1ADRB3 | |
| SCHEMBL4926853 | 0.92 | ITGAL (0.63) | ITGALITGB1ITGA5ADRB1ADRB3 | |
| SCHEMBL19157785 | 0.92 | ITGAL (0.63) | ITGALITGB1ITGA5ADRB1ADRB3 | |
| SCHEMBL18868629 | 0.88 | ITGAL (0.62) | ITGALITGB1ITGA5ADRB1ADRB3 | |
| SCHEMBL15726720 | 0.88 | ITGAL (0.56) | ITGALITGB1ITGA5APLNRITGA4 | |
| SCHEMBL23992520 | 0.87 | ITGAL (0.61) | ITGALITGB1ITGA5ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8168655-B2 | Compositions and methods for treatment of eye disorders | SARCODE BIOSCIENCE INC. (US) | 2012-05-01 | — | — | US | disclosed |