SCHEMBL492281

SCHEMBL492281

C1=CN=COC=C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8123313 0.97
SCHEMBL28008809 0.97
SCHEMBL28527781 0.97
SCHEMBL28529617 0.97
SCHEMBL28518347 0.97
SCHEMBL28587515 0.83
SCHEMBL236152 0.71
SCHEMBL31570731 0.71
SCHEMBL29452703 0.71
SCHEMBL31384562 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 609 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116535329-A Synthetic method of NOBIN-type axial chiral biaryl compound and compound thereof 湖南师范大学 2023-08-04 CN claimed
CN-113185536-B Synthesis method of pyrazolidone benzo 1, 3-oxygen-nitrogen hetero-compound 河南师范大学 2022-06-17 CN claimed
CN-113185536-A Synthesis method of pyrazolidone benzo 1, 3-oxygen-nitrogen hetero-compound 河南师范大学 2021-07-30 CN claimed
CN-109641873-A N- (pyridine -2- base) pyridine-sulfamide derivative and its purposes for disease treatment 诺华股份有限公司 2019-04-16 CN claimed
CN-109311889-A Activin receptor-like kinase inhibitors 蓝图药品公司 2019-02-05 CN claimed
CN-108929336-A Thiazolopyrimidinone class as the active regulator of nmda receptor 豪夫迈·罗氏有限公司 2018-12-04 CN claimed
CN-105612162-B Thiazolopyrimidinones as modulators of NMDA receptor activity 豪夫迈·罗氏有限公司 2018-08-21 CN claimed
CN-108026608-A Method for selective leaching and extraction of precious metals in organic solvents 萨斯喀彻温大学 2018-05-11 CN claimed
CN-104245675-B Cyclic amides as MetAP-2 inhibitors 默克专利股份公司 2017-10-13 CN claimed
CN-104470905-B The miscellaneous azepine * assimilation compounds of substitution 霍夫曼-拉罗奇有限公司 2017-09-12 CN claimed
US-9186461-B2 Viscous formulations and their use in needle-free injection ZOGENIX, INC. (US) 2015-11-17 US claimed
US-8876758-B2 Viscous formulations and their use in needle-free injection ZOGENIX, INC. (US) 2014-11-04 US claimed
US-20120296270-A1 VISCOUS FORMULATIONS AND THEIR USE IN NEEDLE-FREE INJECTION ZOGENIX, INC. 2012-11-22 US claimed
CN-100410250-C Novel spiroheterocyclic compoundsus reversible inhibitors of cysteine proteases BOEHRINGER INGELHEIM PHARMA (US) 2008-08-13 CN claimed
CN-1980931-A Compounds with atypical antipsychotic activity SIGMA TAU IND FARMACEUTI (IT) 2007-06-13 CN claimed
CN-1771237-A 1- (phenylcarbamoyl) -2- (4- (3-oxo-morpholin-4-yl) -phenylcarbamoyl) pyrrolidine derivatives and related compounds as inhibitors of coagulation factor X A in the treatment of thromboembolic disorders MERCK PATENT GMBH (DE) 2006-05-10 CN claimed
US-6774229-B2 PROCESS FOR THE PREPARATION OF AROMATIC OR NON-AROMATIC HETEROCYCLES HAVING FROM 4 TO 10, PREFERABLY FROM 5 TO 7, RING MEMBERS; USED AS FUNGICIDES, ANTIMICROBIALS AND BACTERICIDES MORPHOCHEM AG (DE) 2004-08-10 US claimed
EP-1233944-B1 COUPLING CONDENSATION SYNTHESIS OF HETEROCYCLES MORPHOCHEM AG (DE) 2004-03-31 EP claimed
US-20030100751-A1 Coupling condensation synthesis of heterocycles MORPHOCHEM AG (DE) 2003-05-29 US claimed
US-5413627-A Scrubbing with saturated or unsaturated heterocyclic nitrogen compound, amine, amide, urea, hydrazine, hydrazide, hydrazone functional groups LINDE AKTIENGESELLSCHAFT (DE) 1995-05-09 US claimed