⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL49765 | 0.87 | — | — | |
| SCHEMBL28351490 | 0.75 | — | — | |
| SCHEMBL17491833 | 0.75 | — | — | |
| SCHEMBL28625766 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL641814 | 0.75 | — | — | |
| Bromide SCHEMBL364719 | 0.75 | — | — | |
| SCHEMBL10888412 | 0.75 | — | — | |
| Phosphine SCHEMBL3658909 | 0.75 | — | — | |
| Fluoride SCHEMBL22265126 | 0.75 | — | — | |
| Iodide SCHEMBL4933526 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1341799-B1 | P-CHIRALE BISPHOSPHOLANE LIGANDS, THEIR TRANSITION METAL COMPLEXES | WARNER LAMBERT CO (US) | 2005-03-16 | — | — | EP | claimed |
| US-20030236433-A1 | Synthesis of P-chiral bisphospholane ligands and their transition metal complexes for use as asymmetric hydrogenation catalysts | HOGE GARRETT STEWART (US) | 2003-12-25 | — | — | US | claimed |
| EP-1341799-A1 | P-CHIRALE BISPHOSPHOLANE LIGANDS, THEIR TRANSITION METAL COMPLEXES | Warner-Lambert Company LLC (US) | 2003-09-10 | — | — | EP | claimed |
| US-6605745-B2 | Locates chirality closer to the metal center than known metal phospholane complexes; provide high enantiomeric excesses of formed compounds | HOGE II GARRETT STEWART (US) | 2003-08-12 | — | — | US | claimed |
| US-20020087017-A1 | Synthesis of P-chiral bisphospholane ligands and their transition metal complexes for use as asymmetric hydrogenation catalysts | HOGE GARRETT STEWART (US) | 2002-07-04 | — | — | US | claimed |
| WO-2002048161-A1 | P-CHIRALE BISPHOSPHOLANE LIGANDS, THEIR TRANSITION METAL COMPLEXES | WARNER-LAMBERT COMPANY LLC (US) | 2002-06-20 | — | — | WO | claimed |
| CN-110997686-B | Method for producing 2, 3-biphosphinylpyrazine derivative and method for producing phosphine transition metal complex | 日本化学工业株式会社 | 2023-11-03 | — | — | CN | disclosed |
| CN-112204044-B | Process for producing phosphinobenzeborane derivative, process for producing 1, 2-bis (dialkylphosphino) benzene derivative, and transition metal complex | 日本化学工业株式会社 | 2023-08-29 | — | — | CN | disclosed |
| CN-110709407-B | Method for producing optically active 2, 3-bisphosphinylpyrazine derivative, and method for producing optically active phosphine transition metal complex | 日本化学工业株式会社 | 2022-04-15 | — | — | CN | disclosed |
| EP-3768688-A1 | C-BULKY P-CHIROGENIC ORGANOPHOSPHORUS COMPOUNDS | Université de Bourgogne (FR) | 2021-01-27 | — | — | EP | disclosed |
| US-20200407381-A1 | C-BULKY P-CHIROGENIC ORGANOPHOSPHORUS COMPOUNDS | Université de Bourgogne (FR) | 2020-12-31 | — | — | US | disclosed |
| CN-111868065-A | C-sterically hindered P-chirally derived organophosphorus compounds | 勃艮第大学 | 2020-10-30 | — | — | CN | disclosed |
| WO-2019180084-A1 | C-BULKY P-CHIROGENIC ORGANOPHOSPHORUS COMPOUNDS | Université de Bourgogne (FR) | 2019-09-26 | — | — | WO | disclosed |
| US-6750171-B2 | IMPROVE ENANTIOSELECTIVITY IN ASYMMETRIC REACTIONS | WARNER-LAMBERT COMPANY LLC | 2004-06-15 | — | — | US | disclosed |
| US-20030236433-A1 | Synthesis of P-chiral bisphospholane ligands and their transition metal complexes for use as asymmetric hydrogenation catalysts | HOGE GARRETT STEWART (US) | 2003-12-25 | — | — | US | disclosed |
| EP-1341799-A1 | P-CHIRALE BISPHOSPHOLANE LIGANDS, THEIR TRANSITION METAL COMPLEXES | Warner-Lambert Company LLC (US) | 2003-09-10 | — | — | EP | disclosed |
| US-6605745-B2 | Locates chirality closer to the metal center than known metal phospholane complexes; provide high enantiomeric excesses of formed compounds | HOGE II GARRETT STEWART (US) | 2003-08-12 | — | — | US | disclosed |
| US-20030073868-A1 | Non-C2-symmetric bisphosphine ligands as catalysts for asymmetric hydrogenation | WARNER-LAMBERT COMPANY | 2003-04-17 | — | — | US | disclosed |
| US-20020087017-A1 | Synthesis of P-chiral bisphospholane ligands and their transition metal complexes for use as asymmetric hydrogenation catalysts | HOGE GARRETT STEWART (US) | 2002-07-04 | — | — | US | disclosed |
| WO-2002048161-A1 | P-CHIRALE BISPHOSPHOLANE LIGANDS, THEIR TRANSITION METAL COMPLEXES | WARNER-LAMBERT COMPANY LLC (US) | 2002-06-20 | — | — | WO | disclosed |